YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253522, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	823 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253522, gi|....

Description	E-value	Query Range	Subject Range
gi\|29893824, gi\|... - gi\|30018284\|ref\|NP_829915.1\| DNA gyrase subunit A [Bacillus cereus ATCC 14579], gi\|29893824\|gb\|AAP07...	0.0	[1..810]	[2..811]
gi\|51978672, gi\|... - gi\|52145203\|ref\|YP_081625.1\| DNA gyrase subunit A [Bacillus cereus E33L], gi\|51978672\|gb\|AAU20222.1\|...	0.0	[1..811]	[1..811]
gi\|228716183, gi... - gi\|229065154\|ref\|ZP_04200447.1\| DNA gyrase subunit A [Bacillus cereus AH603], gi\|228716183\|gb\|EEL679... gi\|228647192, gi... - gi\|229136320\|ref\|ZP_04265067.1\| DNA gyrase subunit A [Bacillus cereus BDRD-ST196], gi\|228647192\|gb\|E... gi\|163938019, gi... - gi\|89208021\|ref\|ZP_01186546.1\| DNA gyrase, subunit A [Bacillus weihenstephanensis KBAB4], gi\|8915407...	0.0	[1..809]	[1..809]
gi\|2731385 - gi\|2731385\|gb\|AAB95117.1\| DNA gyrase [Serratia marcescens]	0.0	[1..820]	[1..852]
gi\|77956426, gi\|... - gi\|77956426\|ref\|ZP_00820526.1\| COG0188: Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV...	0.0	[1..821]	[1..853]
gi\|90581243, gi\|... - gi\|90581243\|ref\|ZP_01237041.1\| putative DNA topoisomerase (ATP-hydrolyzing) [Vibrio angustum S14], g...	0.0	[1..822]	[1..866]
gi\|77636493, gi\|... - gi\|77636493\|ref\|ZP_00798567.1\| COG0188: Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV...	0.0	[1..818]	[1..850]
gi\|52078498, gi\|... - gi\|52783862\|ref\|YP_089691.1\| DNA gyrase subunit A [Bacillus licheniformis ATCC 14580], gi\|52346364\|g...	0.0	[1..822]	[1..821]
gi\|238797460, gi... - gi\|77960358\|ref\|ZP_00824233.1\| COG0188: Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV...	0.0	[1..817]	[1..849]
gi\|89202821, gi\|... - gi\|89202821\|ref\|ZP_01181529.1\| DNA gyrase, subunit A [Bacillus cereus subsp. cytotoxis NVH 391-98], ...	0.0	[1..809]	[1..809]

Back

Predicted Domain #1

Region A:
Residues: [1-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNQQQARI REINISHEMR TSFLDYAMSV IVSRALPDVR DGLKPVHRRV LYAMNDLGIT  60
   61 ADKAYKKSAR IVGEVIGKYH PHGDSAVYET MVRMAQDFSQ RYMLVDGHGN FGSVDGDSAA 120
  121 AMRYTEARMS KISMELIRDI SKNTIDYQDN YDGSEREPIV LPARFPNLLV NGTTGIAVGM 180
  181 ATNIPPHQLG EVIDGVLALS HNPDITIAEL MECIPGPDFP TAGLILGRSG IRRAYETGRG 240
  241 SIILRAKVEI EEKSNGKQSI IVTELPYQVN KARLIEKIAE LVRDKKIEGI TDLRDESDRN 300
  301 GMRIVMEVRR DANANVLLNN LYKHTALQTS FGINMLSLVN GEPQVLNLKQ NLYHYLEHQK 360
  361 VVIRRRTAYE LEKAEARAHI LEGLRIALDH LDEVITLIRS SKTAEIAKQG LMERFGLSEK 420
  421 QAQAILDMRL QRLTGLEREK IEQEYQDLMK LIAELKAILA DEEKVLEIIR EELTEVKERF 480
  481 NDKRRTEITI G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ab4A
Description:	59KDA FRAGMENT OF GYRASE A FROM E. COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA topoisomerase activity	16.1862836613251	bayes_pls_golite062009
DNA topoisomerase (ATP-hydrolyzing) activity	15.3845248199845	bayes_pls_golite062009
isomerase activity	11.5598219279347	bayes_pls_golite062009
DNA binding	4.42972615310468	bayes_pls_golite062009
nucleic acid binding	4.21774496265744	bayes_pls_golite062009
binding	3.95084202265591	bayes_pls_golite062009
catalytic activity	1.83123392049501	bayes_pls_golite062009
DNA-dependent ATPase activity	1.17291817800492	bayes_pls_golite062009
protein binding	0.0229806746449869	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [492-823]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMESIEDEDL IPEQNIAITL THNGYIKRLP ASTYKTQNRG GRGVQGMGTN DDDFVEHLLT  60
   61 TSTHDHILFF TNKGKVYRTK GYEIPEYSRT AKGIPIINLL GVDKGEWINA IIPIREFGDD 120
  121 EFLFFTTKQG ISKRTPLSSF ANIRTNGLIA ISLREEDEVI SVRLTSGDKD IIVGTSNGML 180
  181 IRFNEQDVRS MGRNAAGVKA ITLGEEDQVV GMEIVEEDVN VLIVTKNGYG KRTPIDEYRL 240
  241 QSRGGKGLKT CNITDKNGKL VAVKSVTGEE DIMLITAAGV IIRMPVDQIS QMGRNTQGVR 300
  301 LIRLEDEQEV ATVAKAQKDD EEETSEEVSS EE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1zi0A
Description:	A Superhelical Spiral in Escherichia coli DNA Gyrase A C-terminal Domain Imparts Unidirectional Supercoiling Bias
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: