YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264590, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264590, gi|....

Description	E-value	Query Range	Subject Range
gi\|20807045, gi\|... - gi\|20807045\|ref\|NP_622216.1\| 3-hydroxybutyryl-CoA dehydratase [Thermoanaerobacter tengcongensis MB4]... gi\|20807045 - gi\|20807045\|ref\|NP_622216.1\| enoyl-CoA hydratase [Thermoanaerobacter tengcongensis MB4]	4.0E-76	[2..258]	[3..260]
gi\|241218800, gi... - gi\|241769557\|ref\|ZP_04766976.1\| Enoyl-CoA hydratase/isomerase [Sulfolobus solfataricus 98/2], gi\|241... gi\|25291790 - pir\|\|A90436 enoyl CoA hydratase (paaF-7) [imported] - Sulfolobus solfataricus gi\|13815932, gi\|... - gi\|15899349\|ref\|NP_343954.1\| enoyl CoA hydratase (paaF-7) [Sulfolobus solfataricus P2], gi\|13815932\|...	4.0E-75	[1..257]	[8..262]
gi\|15920248, gi\|... - gi\|15920248\|ref\|NP_375917.1\| 3-hydroxybutyryl-CoA dehydrogenase [Sulfolobus tokodaii str. 7], gi\|156...	2.0E-74	[4..257]	[399..651]
gi\|70606884, gi\|... - gi\|70606884\|ref\|YP_255754.1\| 3-hydroxybutyryl-CoA dehydrogenase [Sulfolobus acidocaldarius DSM 639],...	7.0E-74	[3..257]	[409..662]
gi\|28204455, gi\|... - gi\|28212012\|ref\|NP_782956.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium tetani E88], gi\|28204455\|...	2.0E-73	[3..258]	[4..260]
gi\|88926146, gi\|... - gi\|88944140\|ref\|ZP_01147473.1\| putative crotonase [Desulfotomaculum reducens MI-1], gi\|88926146\|gb\|E...	8.0E-73	[4..258]	[5..260]
gi\|116062799, gi... - gi\|118431474\|ref\|NP_147973.2\| 3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase [Aero...	9.0E-73	[2..258]	[413..669]
gi\|1903327 - gi\|1903327\|emb\|CAB07495.1\| crotonase [Thermoanaerobacterium thermosaccharolyticum] gi\|1903327\|emb\|C... - crotonase [Thermoanaerobacterium thermosaccharolyticum]	3.0E-72	[4..255]	[5..257]

Back

Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFLSVRVE DHIAVATLNH APANAMSSQV MHDVTELIDQ VEKDDNIRVV VIHGEGRFFS  60
   61 AGADIKEFTS VTEAKQATEL AQLGQVTFER VEKCSKPVIA AIHGAALGGG LEFAMSCHMR 120
  121 FATESAKLGL PELTLGLIPG FAGTQRLPRY VGKAKACEMM LTSTPITGAE ALKWGLVNGV 180
  181 FAEETFLDDT LKVAKQIAGK SPATARAVLE LLQTTKSSHY YEGVQREAQI FGEVFTSEDG 240
  241 REGVAAFLEK RKPSFSGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.69897
Match:	1ey3A
Description:	Enoyl-CoA hydratase (crotonase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	5.99914207874933	bayes_pls_golite062009
long-chain-enoyl-CoA hydratase activity	5.38361434383109	bayes_pls_golite062009
enoyl-CoA hydratase activity	3.92947460544831	bayes_pls_golite062009
CoA carboxylase activity	3.89913842968597	bayes_pls_golite062009
acetyl-CoA carboxylase activity	3.85567083340773	bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity	3.6090947563188	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	3.4980371783229	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	2.44182589784656	bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity	1.80820904754223	bayes_pls_golite062009
catalytic activity	1.46154163027498	bayes_pls_golite062009
propionyl-CoA carboxylase activity	1.20853698666984	bayes_pls_golite062009
ligase activity	0.98581896521131	bayes_pls_golite062009
binding	0.578223105269736	bayes_pls_golite062009
3-hydroxybutyryl-CoA epimerase activity	0.241955774397835	bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives	0.099208209617217	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	0.0918189681606029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: