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View Structure Prediction Details

Protein: gi|30262746, gi|...
Organism: Bacillus anthracis str. Ames
Length: 398 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30262746, gi|....

Description E-value Query
Range
Subject
Range
gi|126096730, gi... - gi|126207938|ref|YP_001053163.1| dihydrolipoyllysine-residue succinyltransferase component of 2-oxog...
gi|32034768 - gi|32034768|ref|ZP_00134893.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|189914931, gi... - gi|190149800|ref|YP_001968325.1| dihydrolipoyllysine-residue succinyltransferase component of 2-oxog...
0.0 [1..398] [1..407]
gi|85713707, gi|... - gi|85713707|ref|ZP_01044697.1| dihydrolipoamide acetyltransferase [Nitrobacter sp. Nb-311A], gi|8569...
0.0 [3..398] [2..426]
gi|124115754, gi... - gi|153213693|ref|ZP_01948945.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
gi|229528898, gi... - gi|229528898|ref|ZP_04418288.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarat...
gi|229348922, gi... - gi|229513741|ref|ZP_04403203.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarat...
gi|194535435, gi... - gi|75823423|ref|ZP_00752925.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|254286797, gi... - gi|254286797|ref|ZP_04961750.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
tr|D7HAD6|D7HAD6... - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS...
gi|75819459, gi|... - gi|75819459|ref|ZP_00749538.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
0.0 [1..398] [1..402]
gi|227010100, gi... - gi|227082212|ref|YP_002810763.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succin...
gi|229507825, gi... - gi|229507825|ref|ZP_04397330.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarat...
gi|9656634, gi|1... - gi|9656634|gb|AAF95232.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltrans...
gi|229343763, gi... - gi|229519074|ref|ZP_04408517.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarat...
gi|229607370, gi... - gi|229607370|ref|YP_002878018.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutara...
gi|75829400, gi|... - gi|75829400|ref|ZP_00758704.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|147675118, gi... - gi|75827393|ref|ZP_00756828.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|121727380, gi... - gi|75814758|ref|ZP_00745311.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|121586902, gi... - gi|121586902|ref|ZP_01676682.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
gi|124119054, gi... - gi|153222194|ref|ZP_01952973.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
gi|153818382, gi... - gi|153818382|ref|ZP_01971049.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
gi|11257428 - pir||A82121 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase VC2086 ...
gi|229351903, gi... - gi|229511938|ref|ZP_04401417.1| dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarat...
0.0 [1..398] [1..402]
gi|90438940, gi|... - gi|90580055|ref|ZP_01235863.1| dihydrolipoamide acetyltransferase [Vibrio angustum S14], gi|90438940...
0.0 [1..398] [1..399]
gi|89073521, gi|... - gi|89073521|ref|ZP_01160044.1| dihydrolipoamide acetyltransferase [Photobacterium sp. SKA34], gi|890...
0.0 [1..398] [1..399]
gi|28805834 - gi|28805834|dbj|BAC59111.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltra...
gi|153838606, gi... - gi|153838606|ref|ZP_01991273.1| 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succiny...
gi|28805834, gi|... - gi|28897622|ref|NP_797227.1| dihydrolipoamide acetyltransferase [Vibrio parahaemolyticus RIMD 221063...
0.0 [1..398] [1..399]
gi|91188013, gi|... - gi|91228429|ref|ZP_01262354.1| dihydrolipoamide acetyltransferase [Vibrio alginolyticus 12G01], gi|9...
0.0 [1..398] [1..400]
gi|53732513 - gi|53732513|ref|ZP_00154561.2| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|48868188, gi|... - gi|68250263|ref|YP_249375.1| dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydr...
0.0 [1..398] [1..407]
ODO2_HAEIN - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS...
ODO2_HAEIN - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex OS...
0.0 [1..398] [1..407]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVEVVMPKL GMAMKEGIIT SWNIKAGDNV AKGELIASIN SEKIETEIEA PADGTILDIA  60
   61 VSEDEGVPPG TVICYIGKPN EKVEVHESTK VEEELTASEV PQNVQHPEPL GKEVTNKQRI 120
  121 KISPVAKKIA KTENLDIRAL LGTGPGGRIT KVDVLKALEE RVAIPEVLEE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1zy8K
Description: The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [171-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKVLPVTGMR KAIANRMHAS LQNSAQLTLT MKVDVTDLVA LHKEIAEVVQ KRYDNKLTIT  60
   61 DFVSRAVVLA LGEHKEMNSA YIDDAIHQFE HVHLGMAVAL EKGLVVPAIR FANNLSLVEL 120
  121 SKEIKNAAQK ARAGNLNSDD MQGTTFTISN LGSFGIEYFT PVLNTPETGI LGVGAIEHVP 180
  181 VYKGKKLKKG SMLPLSLTFD HRVLDGAPAA AFLRTIKRYL EEPVTILL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.09691
Match: 1c4tA
Description: Dihydrolipoamide succinyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity 9.65061123545754 bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity 9.64995677986911 bayes_pls_golite062009
S-acetyltransferase activity 9.49696044977584 bayes_pls_golite062009
S-acyltransferase activity 8.45313874919036 bayes_pls_golite062009
pyruvate dehydrogenase activity 8.17557182322815 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 6.86215901871647 bayes_pls_golite062009
acyltransferase activity 6.83977352892719 bayes_pls_golite062009
succinyltransferase activity 6.58826720904067 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.40483178382327 bayes_pls_golite062009
acetyltransferase activity 6.08159176722072 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 5.93985773477717 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.60481199262496 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 4.42757758312016 bayes_pls_golite062009
carnitine O-acyltransferase activity 2.87366177129153 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.54513901872655 bayes_pls_golite062009
catalytic activity 1.51562638409295 bayes_pls_golite062009
O-acyltransferase activity 1.33852311685118 bayes_pls_golite062009
O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
carnitine O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
transferase activity 1.08341671157927 bayes_pls_golite062009
carnitine O-acetyltransferase activity 1.00868366840715 bayes_pls_golite062009
binding 0.801074244553007 bayes_pls_golite062009
O-acetyltransferase activity 0.54660034926676 bayes_pls_golite062009
protein binding 0.00454070917775817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle