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View Structure Prediction Details

Protein: gi|30261151, gi|...
Organism: Bacillus anthracis str. Ames
Length: 560 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261151, gi|....

Description E-value Query
Range
Subject
Range
GPDM_BOVIN - Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Bos taurus GN=GPD2 PE=2 SV=1
4.0E-96 [2..560] [51..613]
gi|206743275, gi... - gi|206978515|ref|ZP_03239371.1| glycerol-3-phosphate dehydrogenase, aerobic [Bacillus cereus H3081.9...
gi|42780202, gi|... - gi|42780202|ref|NP_977449.1| glycerol-3-phosphate dehydrogenase, aerobic [Bacillus cereus ATCC 10987...
5.0E-96 [1..560] [1..560]
gi|62988942 - gi|62988942|gb|AAY24329.1| unknown [Homo sapiens]
gi|114581293 - gi|114581293|ref|XP_001142893.1| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
5.0E-96 [2..560] [17..579]
gi|52144287, gi|... - gi|52144287|ref|YP_082541.1| glycerol-3-phosphate dehydrogenase [Bacillus cereus E33L], gi|51977756|...
6.0E-96 [1..560] [1..560]
gi|229183338, gi... - gi|229183338|ref|ZP_04310566.1| FAD dependent oxidoreductase [Bacillus cereus BGSC 6E1], gi|22860012...
gi|49331413, gi|... - gi|49479857|ref|YP_035287.1| glycerol-3-phosphate dehydrogenase [Bacillus thuringiensis serovar konk...
gi|196024932, gi... - gi|196044293|ref|ZP_03111529.1| glycerol-3-phosphate dehydrogenase, aerobic [Bacillus cereus 03BB108...
7.0E-96 [1..560] [1..560]
GPD2 - glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
7.0E-96 [2..560] [51..613]

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Predicted Domain #1
Region A:
Residues: [1-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSSKQRKD VLNGVNKQEL DVIVIGGGIT GSGIALDGAT RGLSTIVFEM QDFAAGTSSR  60
   61 STKLVHGGLR YLKQLEVKMV AEVGKERAIV YENGPHVTTP EWMLLPFHTG GTFGSFSTSI 120
  121 GLRVYDFLAG VKRSERRKMF NREETLKKEP LVKQEGLKGG GYYVEYRTDD ARLTIEVMKE 180
  181 AIEHGAKAVN YAKVDGFLYK DGKVCGVRVI DLLDGEVYEV YGKKIVNAAG PWVDTLREKD 240
  241 NSKKGKVLQL SKGVHLVIDQ KRFPLGQAIY FDTPDKRMVF AIPRGGKTYV GTTDTFYDKD 300
  301 AAVPQMTTED RTYIINAINY MFPSVKITEK DIESSWAGVR PLIYEEGKSA SEISRKDEIW 360
  361 TSESGLITIA GGKLTGYRKM AEMVVDYVTN LLQKEGHSAY PKSSTKHMPI SGGHVDGSKG 420
  421 LPAFIAKKAG EGTKYGLTTA QAEEFAKFYG SNVDVLFDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.39794
Match: 1pj5A
Description: Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 2.25002926602325 bayes_pls_golite062009
electron-transferring-flavoprotein dehydrogenase activity 1.55451764082771 bayes_pls_golite062009
oxidoreductase activity 1.52511707514198 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 1.45104542724719 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 1.35744482443829 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.18990628739838 bayes_pls_golite062009
antioxidant activity 1.12347155061135 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1.08975609376408 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.985237795107607 bayes_pls_golite062009
binding 0.850689563354756 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 0.643810447309487 bayes_pls_golite062009
protein binding 0.370064403093958 bayes_pls_golite062009
NADPH-adrenodoxin reductase activity 0.23045510393832 bayes_pls_golite062009
nucleic acid binding 0.162130833238942 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 0.130601418359425 bayes_pls_golite062009
amine oxidase activity 0.0576694782267841 bayes_pls_golite062009
DNA binding 0.022476246602636 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [460-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKHKDEAKE YNMPLDVLIP LVYAMDYEMT AKPVDFFVRR RGAVFFNIHW VYEWKEAVIN  60
   61 YMAAKLGWSK EEQMKYTAEL EKALTDAVIP VDQQEHAAAL A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.913 0.373 glycerol-3-phosphate metabolic process a.4.5 "Winged helix" DNA-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle