YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253523, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	487 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253523, gi|....

Description	E-value	Query Range	Subject Range
gi\|166853413, gi... - gi\|167039173\|ref\|YP_001662158.1\| response regulator receiver protein [Thermoanaerobacter sp. X514], ... gi\|167038115, gi... - gi\|76796702\|ref\|ZP_00779057.1\| IMP dehydrogenase [Thermoanaerobacter ethanolicus ATCC 33223], gi\|765... gi\|241902681, gi... - gi\|241902681\|ref\|ZP_04787413.1\| inosine-5'-monophosphate dehydrogenase [Thermoanaerobacter brockii s...	0.0	[2..487]	[1..483]
gi\|20807078, gi\|... - gi\|20807078\|ref\|NP_622249.1\| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis MB4],... gi\|20807078 - gi\|20807078\|ref\|NP_622249.1\| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis MB4]	0.0	[2..487]	[1..483]
gi\|56418544, gi\|... - gi\|56418544\|ref\|YP_145862.1\| inositol-5-monophosphate dehydrogenase [Geobacillus kaustophilus HTA426... gi\|229328469, gi... - gi\|229500654\|ref\|ZP_04394306.1\| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. Y412MC52], g... gi\|220706074, gi... - gi\|221090011\|ref\|ZP_03559507.1\| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. Y412MC61], g...	0.0	[1..486]	[1..486]
gi\|217064324, gi... - gi\|217957589\|ref\|YP_002336131.1\| inosine-5'-monophosphate dehydrogenase [Bacillus cereus AH187], gi\|... gi\|51978670, gi\|... - gi\|52145201\|ref\|YP_081627.1\| inositol-5-monophosphate dehydrogenase [Bacillus cereus E33L], gi\|51978... gi\|206978352, gi... - gi\|206978352\|ref\|ZP_03239226.1\| inosine-5'-monophosphate dehydrogenase [Bacillus cereus H3081.97], g... gi\|42735005, gi\|... - gi\|42779090\|ref\|NP_976337.1\| inositol-5-monophosphate dehydrogenase [Bacillus cereus ATCC 10987], gi...	0.0	[1..487]	[1..487]
gi\|49328245, gi\|... - gi\|49476689\|ref\|YP_034368.1\| inositol-5-monophosphate dehydrogenase [Bacillus thuringiensis serovar ...	0.0	[1..487]	[1..487]
gi\|228727407, gi... - gi\|229039917\|ref\|ZP_04189683.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus AH676], gi\|2... gi\|30018286, gi\|... - gi\|30018286\|ref\|NP_829917.1\| inositol-5-monophosphate dehydrogenase [Bacillus cereus ATCC 14579], gi... gi\|228956453, gi... - gi\|228956453\|ref\|ZP_04118251.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|228809103, gi... - gi\|228950560\|ref\|ZP_04112696.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|228840678, gi... - gi\|228918963\|ref\|ZP_04082344.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|218234538, gi... - gi\|218234538\|ref\|YP_002364863.1\| inosine-5'-monophosphate dehydrogenase [Bacillus cereus B4264], gi\|... gi\|228657913, gi... - gi\|229125529\|ref\|ZP_04254563.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus BDRD-Cer4], ... gi\|228675738, gi... - gi\|229107698\|ref\|ZP_04237336.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus Rock1-15], g... gi\|229077285, gi... - gi\|229077285\|ref\|ZP_04209968.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus Rock4-2], gi... gi\|206972681, gi... - gi\|206972681\|ref\|ZP_03233621.1\| inosine-5'-monophosphate dehydrogenase [Bacillus cereus AH1134], gi\|... gi\|229067776, gi... - gi\|229067776\|ref\|ZP_04201095.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus F65185], gi\|... gi\|228595165, gi... - gi\|229188297\|ref\|ZP_04315348.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus ATCC 10876],... gi\|229176612, gi... - gi\|229176612\|ref\|ZP_04304019.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus 172560W], gi... gi\|229148421, gi... - gi\|229148421\|ref\|ZP_04276679.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus m1550], gi\|2... gi\|229142818, gi... - gi\|229142818\|ref\|ZP_04271262.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus BDRD-ST24], ...	0.0	[1..487]	[1..487]
gi\|163860218, gi... - gi\|89208568\|ref\|ZP_01187068.1\| IMP dehydrogenase [Bacillus weihenstephanensis KBAB4], gi\|89153515\|gb...	0.0	[1..487]	[1..487]
gi\|228782933, gi... - gi\|228976771\|ref\|ZP_04137185.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis Bt407... gi\|218545932, gi... - gi\|218895149\|ref\|YP_002443560.1\| inosine-5'-monophosphate dehydrogenase [Bacillus cereus G9842], gi\|... gi\|228789502, gi... - gi\|228970201\|ref\|ZP_04130862.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|75764313, gi\|... - gi\|75764313\|ref\|ZP_00743847.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serova... gi\|228898766, gi... - gi\|228898766\|ref\|ZP_04063050.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis IBL 4... gi\|228937315, gi... - gi\|228937315\|ref\|ZP_04099963.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|228905809, gi... - gi\|228905809\|ref\|ZP_04069708.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis IBL 2...	0.0	[1..487]	[1..487]
gi\|228828133, gi... - gi\|228931515\|ref\|ZP_04094423.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|229089144, gi... - gi\|229089144\|ref\|ZP_04220428.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus Rock3-42], g... gi\|228815843, gi... - gi\|228943819\|ref\|ZP_04106206.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis serov... gi\|229182407, gi... - gi\|229182407\|ref\|ZP_04309660.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus BGSC 6E1], g... gi\|229119675, gi... - gi\|229119675\|ref\|ZP_04248938.1\| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus 95/8201], gi... gi\|65317475 - gi\|65317475\|ref\|ZP_00390434.1\| COG0516: IMP dehydrogenase/GMP reductase [Bacillus anthracis str. A20... gi\|118475786, gi... - gi\|118475786\|ref\|YP_892937.1\| inosine 5'-monophosphate dehydrogenase [Bacillus thuringiensis str. Al...	0.0	[1..487]	[6..492]
gi\|89203316, gi\|... - gi\|89203316\|ref\|ZP_01181997.1\| IMP dehydrogenase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|8...	0.0	[1..487]	[1..487]

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Predicted Domain #1

Region A:
Residues: [1-487]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWESKFVKEG LTFDDVLLVP AKSDVLPREV SVKTVLSESL QLNIPLISAG MDTVTEADMA  60
   61 IAMARQGGLG IIHKNMSIEQ QAEQVDKVKR SESGVISDPF FLTPEHQVYD AEHLMGKYRI 120
  121 SGVPVVNNLD ERKLVGIITN RDMRFIQDYS IKISDVMTKE QLITAPVGTT LSEAEKILQK 180
  181 YKIEKLPLVD NNGVLQGLIT IKDIEKVIEF PNSAKDKQGR LLVGAAVGVT ADAMTRIDAL 240
  241 VKASVDAIVL DTAHGHSQGV IDKVKEVRAK YPSLNIIAGN VATAEATKAL IEAGANVVKV 300
  301 GIGPGSICTT RVVAGVGVPQ LTAVYDCATE ARKHGIPVIA DGGIKYSGDM VKALAAGAHV 360
  361 VMLGSMFAGV AESPGETEIY QGRQFKVYRG MGSVGAMEKG SKDRYFQEGN KKLVPEGIEG 420
  421 RVPYKGPLAD TVHQLVGGLR AGMGYCGAQD LEFLRENAQF IRMSGAGLLE SHPHHVQITK 480
  481 EAPNYSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	1zfjA
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
IMP dehydrogenase activity	2.02048863053452	bayes_pls_golite062009
binding	0.964202692685807	bayes_pls_golite062009
transporter activity	0.961062314616209	bayes_pls_golite062009
transmembrane transporter activity	0.807029018941177	bayes_pls_golite062009
substrate-specific transporter activity	0.640881170978843	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.525366315833255	bayes_pls_golite062009
ion transmembrane transporter activity	0.440262824681055	bayes_pls_golite062009
protein binding	0.22179604283012	bayes_pls_golite062009
catalytic activity	0.181756622780318	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.0973526732376297	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: