YRC Public Data Repository - Protein Structure Prediction

Protein:	UNG_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UNG_COXBU.

Description	E-value	Query Range	Subject Range
UNG_AZOVD - Uracil-DNA glycosylase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=ung PE=3 SV=1 gi\|53611343, gi\|... - gi\|67153345\|ref\|ZP_00415090.1\| Uracil-DNA glycosylase [Azotobacter vinelandii AvOP], ref\|ZP_00090188...	391.0	[0..5]	[228..9]
UNG_RHIME - Uracil-DNA glycosylase OS=Rhizobium meliloti GN=ung PE=3 SV=1 UNG_RHIME - Uracil-DNA glycosylase OS=Rhizobium meliloti (strain 1021) GN=ung PE=3 SV=1	381.0	[0..2]	[228..3]
gi\|110834507, gi... - gi\|110834507\|ref\|YP_693366.1\| uracil-DNA glycosylase [Alcanivorax borkumensis SK2], gi\|110647618\|emb...	380.0	[0..5]	[226..16]
UNG_SINMW - Uracil-DNA glycosylase OS=Sinorhizobium medicae (strain WSM419) GN=ung PE=3 SV=1	379.0	[0..2]	[228..3]
gi\|94268939, gi\|... - gi\|94268939\|ref\|ZP_01291328.1\| Uracil-DNA glycosylase [delta proteobacterium MLMS-1], gi\|94264320\|re...	378.0	[0..2]	[228..23]
gi\|95112272 - gi\|95112272\|emb\|CAK16999.1\| uracil-DNA glycosylase [Pseudomonas entomophila L48] UNG_PSEE4 - Uracil-DNA glycosylase OS=Pseudomonas entomophila (strain L48) GN=ung PE=3 SV=1	378.0	[0..4]	[225..7]
UNG_PSEPK - Uracil-DNA glycosylase OS=Pseudomonas putida (strain KT2440) GN=ung PE=3 SV=1	378.0	[0..4]	[225..7]
gi\|82739988, gi\|... - gi\|82739988\|ref\|ZP_00902762.1\| Uracil-DNA glycosylase [Pseudomonas putida F1], gi\|82712950\|gb\|EAP480...	377.0	[0..4]	[225..53]
gi\|90416423, gi\|... - gi\|90416423\|ref\|ZP_01224354.1\| uracil-DNA glycosylase [marine gamma proteobacterium HTCC2207], gi\|90... gi\|90416423\|ref\|... - uracil-DNA glycosylase [marine gamma proteobacterium HTCC2207]	375.0	[0..4]	[227..9]
UNG_PSEF5 - Uracil-DNA glycosylase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=ung PE=3 SV=1	374.0	[0..4]	[225..7]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTMAETQTW QTVLGEEKQE PYFQEILDFV KKERKAGKII YPPQKDIFNA LKLTPYEAIK  60
   61 VVILGQDPYH GPNQAHGLAF SVRPGVPAPP SLQNIFKELH ADLGVSIPSH GFLEKWAKQG 120
  121 VLLLNAALTV EAGKPQSHAN IGWHRFTDKV IESLNDHPEG IVFLLWGSYA QKKSQLITNL 180
  181 RHRILKAPHP SPLSAARGFL GCRHFSKANQ LLHEMGRGEI DWALDEKVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	1eugA
Description:	Uracil-DNA glycosylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.32235853064174	bayes_pls_golite062009
uracil DNA N-glycosylase activity	4.14707882788321	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.89636585289546	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.84444466513934	bayes_pls_golite062009
hydrolase activity	1.91716804176625	bayes_pls_golite062009
single-strand selective uracil DNA N-glycosylase activity	1.65657095637032	bayes_pls_golite062009
catalytic activity	1.59111295908728	bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity	0.783383667044285	bayes_pls_golite062009
binding	0.587736812286194	bayes_pls_golite062009
structure-specific DNA binding	0.381118322219236	bayes_pls_golite062009
protein binding	0.272261244770552	bayes_pls_golite062009
nucleic acid binding	0.0311777202379154	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: