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View Structure Prediction Details

Protein: gi|24350752, gi|...
Organism: Shewanella oneidensis MR-1
Length: 471 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24350752, gi|....

Description E-value Query
Range
Subject
Range
gi|71488678, gi|... - gi|71545481|ref|ZP_00666412.1| RND efflux system, outer membrane lipoprotein, NodT [Syntrophobacter ...
308.0 [0..23] [449..263]
gi|84357726 - gi|84357726|ref|ZP_00982537.1| COG0841: Cation/multidrug efflux pump [Burkholderia cenocepacia PC184...
283.0 [0..17] [448..1108]
gi|67981567, gi|... - gi|95930203|ref|ZP_01312941.1| Hydrophobe/amphiphile efflux-1 HAE1 [Desulfuromonas acetoxidans DSM 6...
278.0 [0..23] [454..1085]
gi|85858611, gi|... - gi|85858611|ref|YP_460813.1| type I secretion outer membrane protein [Syntrophus aciditrophicus SB],...
278.0 [0..22] [448..85]
gi|46446186, gi|... - gi|46446186|ref|YP_007551.1| putative outer membrane protein, componenet of multidrug efflux systems...
276.0 [0..17] [448..38]
gi|83652156, gi|... - gi|83718331|ref|YP_439482.1| RND efflux system outer membrane lipoprotein [Burkholderia thailandensi...
275.0 [0..17] [465..92]
gi|53753478, gi|... - gi|54293646|ref|YP_126061.1| hypothetical protein lpl0699 [Legionella pneumophila str. Lens], gi|537...
275.0 [0..21] [457..51]
gi|91785070, gi|... - gi|91785070|ref|YP_560276.1| RND efflux system outer membrane lipoprotein [Burkholderia xenovorans L...
274.0 [0..17] [465..68]
gi|94731686, gi|... - gi|94987437|ref|YP_595370.1| outer membrane efflux protein [Lawsonia intracellularis PHE/MN1-00], gi...
273.0 [0..19] [449..44]

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Predicted Domain #1
Region A:
Residues: [1-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLVRRQFQ CSKIAVLLSA ILLPLSAQSQ TLEQAVAHTL DTNPDLRVAF NRFKAREEQV  60
   61 NQAIAGYMPT VDLTGGYGYE QTDSVSTRRR KNVGDVDSNG VAELNRGEFG ISLKQMLFDG 120
  121 FYTSSEVDRY SFEASADQWA LLAAAEDMAL DVSKAYLNYL RTDEVLKLAE KNLNSHKEIY 180
  181 DQIKQRTDSG LGSTADLSQI SGRLARANAN VISARNNLLD AKAQFVRVVA ADPVDLIQPV 240
  241 PDADMLPKDL NSSIADAEKN HPILKSAAND IRAAENERSS TQANYYPQVS LELNGSWNND 300
  301 VGGEDGVSAI ASQNVGGYSN DIVAMVRVKY NLFAGGKDLA REKESAYKLS EAKEIRQRAQ 360
  361 REVVEGVNLA WNAYEMLAPQ KQYIRDHVIA AKDTQSAYAQ QFNLGQRSLL DLLDTENELF 420
  421 EARKDYLQAE YDETIAKYRV LNSTGRLLDS LKVTRPEAWR GERNYEGGAN Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.39794
Match: 1wp1A
Description: Crystal structure of the drug-discharge outer membrane protein, OprM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.2806100513341 bayes_pls_golite062009
transmembrane transporter activity 2.91628575119399 bayes_pls_golite062009
porin activity 0.960340223825989 bayes_pls_golite062009
protein binding 0.733559018445359 bayes_pls_golite062009
binding 0.666039242029224 bayes_pls_golite062009
drug transmembrane transporter activity 0.40205797321583 bayes_pls_golite062009
efflux transmembrane transporter activity 0.381147202210091 bayes_pls_golite062009
0.32815814791941 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle