YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374925, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	822 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374925, gi|....

Description	E-value	Query Range	Subject Range
gi\|22127591, gi\|... - gi\|22127591\|ref\|NP_671014.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pesti...	757.0	[0..1]	[820..27]
gi\|77631588, gi\|... - gi\|77631588\|ref\|ZP_00794174.1\| COG0527: Aspartokinases [Yersinia pseudotuberculosis IP 31758], gi\|15... gi\|169752353, gi... - gi\|170025819\|ref\|YP_001722324.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia p...	757.0	[0..1]	[820..1]
gi\|16120788, gi\|... - gi\|218927656\|ref\|YP_002345531.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia p... gi\|162351497, gi... - gi\|77635662\|ref\|ZP_00797744.1\| COG0527: Aspartokinases [Yersinia pestis Angola], gi\|162418682\|ref\|YP... gi\|165920737, gi... - gi\|165927275\|ref\|ZP_02223107.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|166009003, gi... - gi\|166009003\|ref\|ZP_02229901.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|166211875, gi... - gi\|166211875\|ref\|ZP_02237910.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|167401565, gi... - gi\|167401565\|ref\|ZP_02307059.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|167418972, gi... - gi\|167418972\|ref\|ZP_02310725.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|165915554, gi... - gi\|89104422\|ref\|ZP_01176966.1\| COG0527: Aspartokinases [Yersinia pestis biovar Orientalis str. IP275... gi\|167426040, gi... - gi\|167426040\|ref\|ZP_02317793.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|108810041, gi... - gi\|108810041\|ref\|YP_653957.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pest... gi\|167468965 - gi\|167468965\|ref\|ZP_02333669.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pe... gi\|229682023, gi... - gi\|229900684\|ref\|ZP_04515808.1\| bifunctional aspartokinase I/homoserine dehydrogenase I [Yersinia pe... gi\|186893955, gi... - gi\|186893955\|ref\|YP_001871067.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia p... gi\|229013121 - gi\|229013121\|ref\|NP_671014.2\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pest... Q66ET9\|Q66ET9_YERPS - Bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I - Yersinia pseudotuberculosis gi\|229220775 - gi\|229220775\|ref\|NP_994994.2\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pest... gi\|229705903, gi... - gi\|229836960\|ref\|ZP_04457125.1\| bifunctional aspartokinase I/homoserine dehydrogenase I [Yersinia pe... gi\|229696710, gi... - gi\|229840344\|ref\|ZP_04460503.1\| bifunctional aspartokinase I/homoserine dehydrogenase I [Yersinia pe... gi\|229842424, gi... - gi\|229842424\|ref\|ZP_04462579.1\| bifunctional aspartokinase I/homoserine dehydrogenase I [Yersinia pe... gi\|149289913, gi... - gi\|150260505\|ref\|ZP_01917233.1\| bifunctional aspartokinase/homoserine dehydrogenase I [Yersinia pest... gi\|145600429, gi... - gi\|145600429\|ref\|YP_001164505.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia p... gi\|51594953, gi\|... - gi\|51594953\|ref\|YP_069144.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pseud... gi\|25288159 - pir\|\|AH0056 aspartate kinase (EC 2.7.2.4) [imported] - Yersinia pestis (strain CO92)	755.0	[0..1]	[820..1]
gi\|77961949, gi\|... - gi\|77961949\|ref\|ZP_00825777.1\| COG0527: Aspartokinases [Yersinia mollaretii ATCC 43969], gi\|23879752...	750.0	[0..1]	[820..1]
gi\|45438324, gi\|... - gi\|45443455\|ref\|NP_994994.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pesti...	750.0	[0..4]	[820..2]
gi\|238795005, gi... - gi\|77976936\|ref\|ZP_00832401.1\| COG0527: Aspartokinases [Yersinia intermedia ATCC 29909], gi\|23879500...	748.0	[0..1]	[820..1]
AK1H_SERMA - Bifunctional aspartokinase/homoserine dehydrogenase 1 OS=Serratia marcescens GN=thrA PE=3 SV=1	747.0	[0..1]	[820..1]

Back

Predicted Domain #1

Region A:
Residues: [1-462]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVMKFGGTS LANWQRFSMA ADIVAKAATM EPVATVLSAP ATVTNALLEM VNLAVKGEDY  60
   61 SPVIQHVERV FTSLYQDAVS SGLSSTQSEL LFAGLGAQLA RWQDRLHGIT LLQECPDGIC 120
  121 AEIVVAGERL SAALMEQVML AKGITSAQLD PRKLFLGRGR PLESVVDIAV SKPRFKNLLL 180
  181 DEKRVWVMPG FTAADEDGKV VTLGRNGSDY SAAVLAACLD ASSCEIWTDV DGVYNTDPRV 240
  241 VADAKLLSQL SYQEAMELSY FGAKVLHPKT IAPIAQFHIP CYIKNSFNPD APGTLVSNLA 300
  301 DASGLQVKAI SNLDNQTMFD VSGPGMKGMV GMASRTLAAI SRSGVSVSLI TQSSCEYSIS 360
  361 FCVATSESAK VKLALEQEFE LEIKSDLLEP IEMRHDLAIV SLIGDGMRTH KGVAARFFQA 420
  421 LAQASVNIIA IAQGSSERSI STVIEQRKTK HAVAACHQGF FD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	101.0
Match:	2hmfA
Description:	No description for 2hmfA was found.

Predicted functions:

Term	Confidence	Notes
kinase activity	3.6039877609535	bayes_pls_golite062009
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	3.26420758063619	bayes_pls_golite062009
aspartate kinase activity	3.23731032633773	bayes_pls_golite062009
transferase activity	3.047646907595	bayes_pls_golite062009
catalytic activity	2.83338756483354	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	2.65970393362911	bayes_pls_golite062009
transcription regulator activity	2.54193538468834	bayes_pls_golite062009
amino acid kinase activity	2.38310367076654	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.27460110663386	bayes_pls_golite062009
nucleic acid binding	1.77420728550693	bayes_pls_golite062009
DNA binding	1.70654139251388	bayes_pls_golite062009
binding	1.61057316956254	bayes_pls_golite062009
acetylglutamate kinase activity	1.28891782911186	bayes_pls_golite062009
transcription factor activity	1.13755026342338	bayes_pls_golite062009
transcription repressor activity	0.61058430787131	bayes_pls_golite062009
glutamate 5-kinase activity	0.416864856459166	bayes_pls_golite062009
protein binding	0.178881469836152	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [463-822]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQQYLDVFLV GCGNVGAGLL EQIKQQAIVL KEQHISIRVC GIVNSSKMLL DSAGIDLNNW  60
   61 QNLLADSQQS SDLPALLAWV KEQQLLNPVL VDCTSSEQVS NQYLEVMNAG MHVVTPNKKA 120
  121 NTRDYAYYQA LRQTALTQRR QFLYETNVGA GLPVIDNLKK LLFAGDKLHK FNGILSGSLS 180
  181 FIFGKLDEGM SLSEATKLAR EKCFTEPDPR DDLSGMDVAR KVLILAREVG LKLELSDIVV 240
  241 DSVLPESFDD SGDVESFMAR LPEADAAIAA RVAEAKAQGK VLRYVGQIEE GACHVRIAEV 300
  301 DATDPLYSVK GGENALAFYS RYYQPIPFVL RGYGAGTEVT AAGAFADVLR TLNWTREVSV 360
  361

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.39794
Match:	1ebfA
Description:	Homoserine dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.54843319568228	bayes_pls_golite062009
transcription regulator activity	1.90939908578582	bayes_pls_golite062009
oxidoreductase activity	1.84451425136793	bayes_pls_golite062009
DNA binding	1.61355789916908	bayes_pls_golite062009
nucleic acid binding	1.48478425318425	bayes_pls_golite062009
binding	1.22114607236074	bayes_pls_golite062009
transcription factor activity	0.91090893050278	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.610531769148819	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.610013758225609	bayes_pls_golite062009
saccharopine dehydrogenase activity	0.495113665163626	bayes_pls_golite062009
structural molecule activity	0.345975336806588	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.0651785123513661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: