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Protein Overview: gi|229220775

General Information:
Name(s) found: gi|229220775 [NCBI NR]
Description(s) found:
  • gi|229220775|ref|NP_994994.2| bifunctional aspartokinase I/homeserine dehydrogenase I [Yersinia pestis biovar Microtus str. 91001] [NCBI NR]
    • Organism: Yersinia pestis biovar Microtus str. 91001
    Length: 819 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLKFGGTS VANAERFMRV ADIIESNARQ GQVATVLSAP AKITNHLVAM IDKMVAGQDI  60
   61 SPNISDAERI FAELLRGLAD TQPGFDYDRL KALVGHEFAQ LKHLLHGISL LGQCPDSINA 120
  121 SIICRGEKLS IAIMEALFQA KGYHVTVINP VEKLLAQGHY LESTVDITES TRRIGASGIP 180
  181 SDHIILMAGF TAGNDKGELV VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRTV 240
  241 PDARLLKSMS YQEAMELSYF GAKVLHPRTI APIARFQIPC LIKNTSNPQA PGTLIGGESI 300
  301 DEDSPVKGIT NLNNMAMINV SGPGMKGMVG MAARVFAVMS RSGISVVLIT QSSSEYSISF 360
  361 CVPQGELLRA RRALEDEFYL ELKDGVLDPL DVMEHLAIIS VVGDGMRTLR GISARFFSAL 420
  421 ARANINIIAI AQGSSERSIS VVVNNDAVTT GVRVCHQMLF NTDQVIEVFV IGVGGVGGAL 480
  481 IEQIYRQQPW LKQRHIDLRV CGIANSKAML TNVHGIALDN WRQELAEVQE PFNLSRLIRL 540
  541 VKEYHLLNPV IVDCTSSQAV ADQYADFLTD GFHVVTPNKK ANTSSMNYYR QMRAAATKSC 600
  601 RKFLYDTNVG AGLPVIENLQ NLLNAGDELM RFTGILSGSL SFIFGKLDEG MSLSEATRQA 660
  661 KALGYTEPDP RDDLSGMDVA RKLLILAREA GYKLELADIE VESVLPASFD ASGDVDTFLA 720
  721 RLPSLDAEFT RLVANAAEQG KVLRYVGVIE DGRCKVRMEA VDGNDPLYKV KNGENALAFY 780
  781 TRYYQPIPLV LRGYGAGNDV TAAGVFADLL RTLSWKLGV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..463] PSI-BLAST 99.0 No description for 2hmfA was found.
    2 View Details [464..819] PSI-BLAST 73.39794 Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aspartate kinase activity
    		•  3.23731032633773 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  3.23518662935565 bayes_pls_golite062009
  • catalytic activity
    		•  2.83338756483354 bayes_pls_golite062009
  • phosphotransferase activity, carboxyl group as acceptor
    		•  2.65970393362911 bayes_pls_golite062009
  • amino acid kinase activity
    		•  2.38310367076654 bayes_pls_golite062009
  • transferase activity
    		•  2.34413838821786 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.27460110663386 bayes_pls_golite062009
  • kinase activity
    		•  2.21185047886997 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.13438534889644 bayes_pls_golite062009
  • acetylglutamate kinase activity
    		•  1.28891782911186 bayes_pls_golite062009
  • glutamate 5-kinase activity
    		•  0.416864856459166 bayes_pls_golite062009
  • binding
    		•  0.416787048641206 bayes_pls_golite062009
    2
    Term Confidence Notes
  • oxidoreductase activity
    		•  2.60548927745815 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.41676087939212 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.841370849960815 bayes_pls_golite062009
  • phosphoglycerate dehydrogenase activity
    		•  0.639509916626856 bayes_pls_golite062009
  • saccharopine dehydrogenase activity
    		•  0.495113665163626 bayes_pls_golite062009
  • N-acetyl-gamma-glutamyl-phosphate reductase activity
    		•  0.0651785123513661 bayes_pls_golite062009
  • binding
    		•  0.0273599514394109 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle