YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374773, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	581 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374773, gi|....

Description	E-value	Query Range	Subject Range
gi\|88602528, gi\|... - gi\|88602528\|ref\|YP_502706.1\| acetolactate synthase, large subunit, biosynthetic type [Methanospirill...	515.0	[0..6]	[566..1]
gi\|21226772, gi\|... - gi\|21226772\|ref\|NP_632694.1\| acetolactate synthase 3 catalytic subunit [Methanosarcina mazei Go1], g...	513.0	[0..1]	[572..1]
gi\|17232105, gi\|... - gi\|17232105\|ref\|NP_488653.1\| acetolactate synthase 3 catalytic subunit [Nostoc sp. PCC 7120], gi\|171... gi\|25291313 - pir\|\|AE2382 acetohydroxy acid synthase [imported] - Nostoc sp. (strain PCC 7120)	512.0	[0..3]	[567..29]
gi\|75908969, gi\|... - gi\|75908969\|ref\|YP_323265.1\| acetolactate synthase 3 catalytic subunit [Anabaena variabilis ATCC 294...	512.0	[0..3]	[567..29]
gi\|77996676, gi\|... - gi\|78044561\|ref\|YP_359375.1\| acetolactate synthase, large subunit, biosynthetic type [Carboxydotherm...	511.0	[0..5]	[567..1]
gi\|72394929, gi\|... - gi\|73667767\|ref\|YP_303782.1\| acetolactate synthase 3 catalytic subunit [Methanosarcina barkeri str. ...	509.0	[0..1]	[575..1]
gi\|227815330, gi... - gi\|227815330\|ref\|YP_002815339.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus a... gi\|228832625, gi... - gi\|228926890\|ref\|ZP_04089956.1\| hypothetical protein bthur0010_16060 [Bacillus thuringiensis serovar... gi\|229121439, gi... - gi\|229121439\|ref\|ZP_04250666.1\| hypothetical protein bcere0016_17430 [Bacillus cereus 95/8201], gi\|2... gi\|167633267, gi... - gi\|167633267\|ref\|ZP_02391592.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|229264419, gi... - gi\|229600011\|ref\|YP_002866266.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus a... gi\|165869277, gi... - gi\|165869277\|ref\|ZP_02213936.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|254684449 - gi\|254684449\|ref\|ZP_05148309.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. C... gi\|49184727, gi\|... - gi\|49184727\|ref\|YP_027979.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. Ster... gi\|170686210, gi... - gi\|170686210\|ref\|ZP_02877432.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|254723976 - gi\|254723976\|ref\|ZP_05185762.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. A... gi\|47502289, gi\|... - gi\|47527141\|ref\|YP_018490.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. 'Ame... gi\|167513323, gi... - gi\|167638859\|ref\|ZP_02397134.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|254734751 - gi\|254734751\|ref\|ZP_05192463.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. W... gi\|177650607, gi... - gi\|177650607\|ref\|ZP_02933574.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|254741154 - gi\|254741154\|ref\|ZP_05198842.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. K... gi\|170127803, gi... - gi\|170707304\|ref\|ZP_02897759.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|254755402 - gi\|254755402\|ref\|ZP_05207436.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. V... gi\|218903005, gi... - gi\|218903005\|ref\|YP_002450839.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus c... gi\|254759940 - gi\|254759940\|ref\|ZP_05211964.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. A... gi\|190562476, gi... - gi\|190566341\|ref\|ZP_03019259.1\| acetolactate synthase, large subunit, biosynthetic type [Bacillus an... gi\|30261891, gi\|... - gi\|30261891\|ref\|NP_844268.1\| acetolactate synthase 3 catalytic subunit [Bacillus anthracis str. Ames... gi\|65319169, gi\|... - gi\|65319169\|ref\|ZP_00392128.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth...	507.0	[0..5]	[569..13]
gi\|49481115, gi\|... - gi\|49481115\|ref\|YP_036023.1\| acetolactate synthase 3 catalytic subunit [Bacillus thuringiensis serov...	507.0	[0..5]	[569..13]
gi\|219993234, gi... - gi\|89210057\|ref\|ZP_01188450.1\| Acetolactate synthase, large subunit, biosynthetic type [Halothermoth...	507.0	[0..4]	[567..1]
gi\|7436698 - pir\|\|C70341 acetolactate synthase (EC 4.1.3.18) large chain - Aquifex aeolicus gi\|15605942, gi\|... - gi\|2983101\|gb\|AAC06706.1\| acetolactate synthase large subunit [Aquifex aeolicus VF5], gi\|15605942\|re...	506.0	[0..4]	[579..1]

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Predicted Domain #1

Region A:
Residues: [1-581]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSPITVVA DAIIEFLAHQ GIKAFHNYPG GTIAPLLDAC KRFGVTVYTS RNEQGAGYAA  60
   61 LAQGKLTQLP GIVAVTSGPG VTNVLTPVAD AYFDGIPMLV FTGQVGTGDL TGQKRVRQSG 120
  121 FQEVDTPSLM KPITKGQFQP KNSEELYAIL PIAWQLALEG RKGPVSIDLP MDVQRSAAIK 180
  181 SIKVPEIVTY PVNRTELGTF IDELINAIDH SQKPVIICGN GMTSPALVDA IRTLRNYWPA 240
  241 PVSHSLLGVG VLDTDDSGSL GFHGHTGSQL AGKAIAECDL LLVLGSRLDV RQTGTLKTAF 300
  301 ASNAKIFRVD LDIGELTDSR IAHHKAVQAE LEQFFDALHP KFAQLSPPNL SSWHNTISQW 360
  361 KAQLAWPYPD YPGIAPKLLL EKLSNSLPEN TIVTTGVGAH QHWVARHFRF ALPHRQLFTS 420
  421 AGHGTMGYDL PTAIGAAIHS PESTILCIAG DGSFQMNIQE LGVIKELGLK IKILVLDNHR 480
  481 LGLVSQFQLM NWETDTACGN KQSPNFALIA QGYGIKALHC SDSAKLEQTL AEFIETDESI 540
  541 LLHIEIATQH DVLPMLLGGQ TTDKMWPYFD MQGNPRDPSN V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	129.0
Match:	1ybhA
Description:	Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide Chlorimuron Ethyl
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	12.903449876837	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	12.3239025230705	bayes_pls_golite062009
pyruvate dehydrogenase activity	5.28857071459273	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	5.21233670052586	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	5.08663245333808	bayes_pls_golite062009
transketolase activity	2.50501741089295	bayes_pls_golite062009
catalytic activity	2.25537597692103	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.15444163802756	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.98546381612935	bayes_pls_golite062009
thiamin pyrophosphate binding	1.87247313698582	bayes_pls_golite062009
oxidoreductase activity	1.85833680148029	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.82969293063325	bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	1.65348126142808	bayes_pls_golite062009
deoxyhypusine synthase activity	1.46517585302326	bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity	1.20517690263403	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.0611726850452	bayes_pls_golite062009
protein deacetylase activity	1.00103393476979	bayes_pls_golite062009
histone deacetylase activity	0.99977365092061	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.982646671777	bayes_pls_golite062009
cation transmembrane transporter activity	0.78591260444574	bayes_pls_golite062009
binding	0.551586872853971	bayes_pls_golite062009
hydrolase activity	0.536729211484905	bayes_pls_golite062009
ion transmembrane transporter activity	0.51426028502998	bayes_pls_golite062009
transferase activity	0.413024577830522	bayes_pls_golite062009
NAD-dependent protein deacetylase activity	0.38348854354211	bayes_pls_golite062009
NAD-dependent histone deacetylase activity	0.38348854354211	bayes_pls_golite062009
deacetylase activity	0.382228826641711	bayes_pls_golite062009
transcription regulator activity	0.273969473413919	bayes_pls_golite062009
pyruvate decarboxylase activity	0.198062360371269	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.114062221123972	bayes_pls_golite062009
nucleic acid binding	0.0424046736878951	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: