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View Structure Prediction Details

Protein: gi|24349408, gi|...
Organism: Shewanella oneidensis MR-1
Length: 477 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24349408, gi|....

Description E-value Query
Range
Subject
Range
gi|59480562, gi|... - gi|59712461|ref|YP_205237.1| two-component response regulator FlrC [Vibrio fischeri ES114], gi|59480...
334.0 [0..5] [475..3]
gi|78221996, gi|... - gi|78221996|ref|YP_383743.1| two component, sigma54 specific, Fis family transcriptional regulator [...
333.0 [0..2] [475..1]
gi|222054817, gi... - gi|222054817|ref|YP_002537179.1| two component, sigma54 specific, transcriptional regulator, Fis fam...
333.0 [0..7] [477..5]
gi|85774842, gi|... - gi|86158331|ref|YP_465116.1| two component, sigma54 specific, Fis family transcriptional regulator [...
333.0 [0..5] [474..1]
gi|108757141, gi... - gi|108757141|ref|YP_631748.1| sigma-54 dependent DNA-binding response regulator [Myxococcus xanthus ...
332.0 [0..5] [474..1]
gi|88918223, gi|... - gi|88934958|ref|ZP_01140596.1| Helix-turn-helix, Fis-type [Geobacter uraniumreducens Rf4], gi|889182...
331.0 [0..7] [477..5]
gi|77546022, gi|... - gi|77919939|ref|YP_357754.1| two component signal transduction response regulator [Pelobacter carbin...
331.0 [0..5] [477..1]
gi|46581622, gi|... - gi|46581622|ref|YP_012430.1| sigma-54 dependent transcriptional regulator/response regulator [Desulf...
gi|241908558, gi... - gi|241908558|ref|ZP_04793124.1| two component, sigma54 specific, transcriptional regulator, Fis fami...
331.0 [0..2] [475..1]
gi|39982871, gi|... - gi|39996106|ref|NP_952057.1| nitrogen regulation protein NR(I) [Geobacter sulfurreducens PCA], gi|39...
330.0 [0..7] [475..5]
gi|120601219, gi... - gi|120601219|ref|YP_965619.1| two component, sigma54 specific, Fis family transcriptional regulator ...
330.0 [0..2] [475..1]

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Predicted Domain #1
Region A:
Residues: [1-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQTDQRILL VGTPSERLSR LCCIFEFLGE QIDIITIEKL STCLQETRFR ALVISIDNMS  60
   61 ADALKLVASQ YPWQPILLFG HVGELQVSNV LGHIEEPLNY PQLTELLHFC QVYGQVKRPQ 120
  121 VPTSANQTKL FRSLVGRSDG IANVRHLISQ VATSDATVLV LGQSGTGKEV VARNIHYLSE 180
  181 RRDGPFIPVN CGAIPPELLE SELFGHEKGS FTGAISSRKG RFELAEGGTL FLDEIGDMPL 240
  241 QMQVKLLRVL QERVFERVGG TKTINADVRV VAATHRDLET MISSNEFRED LYYRLNVFPI 300
  301 EMPALSERKD DVPLLLQELV SRVYNEGRGK VRFTQRAIES LKEHAWSGNV RELSNLVERL 360
  361 TILYPGGLVD VNDLPIKYRH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.30103
Match: 1ny5A
Description: Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.95073642969863 bayes_pls_golite062009
pyrophosphatase activity 1.91141407779641 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.9017593265179 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.90014393273511 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.82370030183942 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.79922369980544 bayes_pls_golite062009
transporter activity 1.55572428045529 bayes_pls_golite062009
amino acid transmembrane transporter activity 1.52217781539459 bayes_pls_golite062009
ATPase activity 1.48474288797022 bayes_pls_golite062009
two-component response regulator activity 1.45919623810582 bayes_pls_golite062009
amine transmembrane transporter activity 1.4031990658196 bayes_pls_golite062009
transmembrane transporter activity 1.38483976298883 bayes_pls_golite062009
ATPase activity, coupled 1.37457738689583 bayes_pls_golite062009
catalytic activity 1.37148167194523 bayes_pls_golite062009
binding 1.30574971150356 bayes_pls_golite062009
active transmembrane transporter activity 1.24278046928678 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.2014318795788 bayes_pls_golite062009
primary active transmembrane transporter activity 1.19670408144267 bayes_pls_golite062009
hydrolase activity 1.18053993810305 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1.17063957238561 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 1.16918853509059 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 1.16885789920943 bayes_pls_golite062009
nucleic acid binding 0.900561861643259 bayes_pls_golite062009
transcription regulator activity 0.530058973650498 bayes_pls_golite062009
purine ribonucleotide binding 0.5127850474754 bayes_pls_golite062009
ribonucleotide binding 0.51230334374838 bayes_pls_golite062009
purine nucleotide binding 0.50688037036449 bayes_pls_golite062009
nucleotide binding 0.49473184426584 bayes_pls_golite062009
DNA binding 0.460315660888175 bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity 0.32754685224555 bayes_pls_golite062009
amine-transporting ATPase activity 0.128277449580549 bayes_pls_golite062009
amino acid-transporting ATPase activity 0.109938795198381 bayes_pls_golite062009
substrate-specific transporter activity 0.0838665746103899 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [381-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDVPEYSVEL SEEQQERDAL ASIFTSEEPV EIPETRFPSE LPPEGVNLKD LLAELEIDMI  60
   61 RQALEQQDNV VARAAEMLGI RRTTLVEKMR KYGMTKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.154902
Match: 1ojlA
Description: Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle