YRC Public Data Repository - Protein Structure Prediction

Protein:	ARLY_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	455 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARLY_SHEON.

Description	E-value	Query Range	Subject Range
ARLY_CALS4 - Argininosuccinate lyase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JC... ARLY_THETN - Argininosuccinate lyase OS=Thermoanaerobacter tengcongensis GN=argH PE=3 SV=1	484.0	[0..1]	[440..1]
gi\|221320131 - gi\|221320131\|ref\|ZP_03601425.1\| argininosuccinate lyase [Bacillus subtilis subsp. subtilis str. JH64... gi\|221324413 - gi\|221324413\|ref\|ZP_03605707.1\| argininosuccinate lyase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221315213 - gi\|221315213\|ref\|ZP_03597018.1\| argininosuccinate lyase [Bacillus subtilis subsp. subtilis str. NCIB... ARLY_BACSU - Argininosuccinate lyase OS=Bacillus subtilis (strain 168) GN=argH PE=3 SV=1 ARLY_BACSU - Argininosuccinate lyase OS=Bacillus subtilis GN=argH PE=3 SV=1	483.0	[0..2]	[454..3]
ARLY_CLOTH - Argininosuccinate lyase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NC... gi\|196251693, gi... - gi\|196251693\|ref\|ZP_03150360.1\| argininosuccinate lyase [Clostridium thermocellum DSM 4150], gi\|1961...	483.0	[0..1]	[451..1]
ARLY_BACCN - Argininosuccinate lyase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98...	482.0	[0..2]	[453..3]
ARLY_BACWK - Argininosuccinate lyase OS=Bacillus weihenstephanensis (strain KBAB4) GN=argH PE=3 SV=1	482.0	[0..2]	[453..3]
ARLY_BACCR - Argininosuccinate lyase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCI...	480.0	[0..2]	[453..3]
ARLY_SHIDS - Argininosuccinate lyase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=argH PE=3 SV=1	480.0	[0..1]	[454..1]
gi\|193063986, gi... - gi\|75258056\|ref\|ZP_00729517.1\| COG0165: Argininosuccinate lyase [Escherichia coli E22], gi\|193063986... gi\|75238405, gi\|... - gi\|75238405\|ref\|ZP_00722404.1\| COG0165: Argininosuccinate lyase [Escherichia coli E110019], gi\|19306... gi\|194412550, gi... - gi\|75209354\|ref\|ZP_00709590.1\| COG0165: Argininosuccinate lyase [Escherichia coli B171], gi\|19442940... ARLY_ECO24 - Argininosuccinate lyase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=argH PE=3 SV=1 ARLY_ECO8A - Argininosuccinate lyase OS=Escherichia coli O8 (strain IAI1) GN=argH PE=3 SV=1 ARLY_ECO55 - Argininosuccinate lyase OS=Escherichia coli (strain 55989 / EAEC) GN=argH PE=3 SV=1 ARLY_ECOSE - Argininosuccinate lyase OS=Escherichia coli (strain SE11) GN=argH PE=3 SV=1	480.0	[0..1]	[454..1]
gi\|148545463, gi... - gi\|82737852\|ref\|ZP_00900696.1\| Argininosuccinate lyase [Pseudomonas putida F1], gi\|82715091\|gb\|EAP50...	479.0	[0..4]	[454..45]
ARLY_SHIBS - Argininosuccinate lyase OS=Shigella boydii serotype 4 (strain Sb227) GN=argH PE=3 SV=1	479.0	[0..1]	[454..1]

Back

Predicted Domain #1

Region A:
Residues: [1-455]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWGGRFQG ETSALFKLFN DSLPVDYRLF EQDVVGSIAW ADAIASVGII TATECSDLKK  60
   61 ALNELLVEVK GDPAIILASG AEDIHSFVES ALIAKVGDLG KKLHTGRSRN DQVATDLKLW 120
  121 CQSEGAALVA RLQTLRSELI ALAEREFDAV MPGYTHLQRA QPVTFGHWCL AYVEMIERDF 180
  181 SRLTDALKRA NTCPLGSGAL AGTAYQMDRH ALALALNFAS PTLNSLDSVS DRDHVVELCS 240
  241 TASISMMHLS RMAEDLIFFN TGEAGFISLS DEVTSGSSLM PQKKNPDALE LIRGKTGRVY 300
  301 GSLVGILTTM KALPLAYNKD MQEDKEGLFD VVDSWAICLD MAALVLSGLV VNRPNALLAA 360
  361 QQGYANATEL ADYLVSKGMP FREAHHVVGV AVVAAIAKKI PLEGFTLAEF KTFADIIEDD 420
  421 VYPNLTIEAC LAKRDVLGGT ALTQVKQAIA AKKAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	135.0
Match:	1tj7A
Description:	Structure determination and refinement at 2.44 A resolution of Argininosuccinate lyase from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
amidine-lyase activity	3.84281419858187	bayes_pls_golite062009
argininosuccinate lyase activity	3.58328346705456	bayes_pls_golite062009
catalytic activity	2.51282259572665	bayes_pls_golite062009
lyase activity	2.31268471569846	bayes_pls_golite062009
carbon-nitrogen lyase activity	2.2046475419807	bayes_pls_golite062009
fumarate hydratase activity	1.8220456742683	bayes_pls_golite062009
histidine ammonia-lyase activity	0.948129236753279	bayes_pls_golite062009
binding	0.616567403608599	bayes_pls_golite062009
ammonia-lyase activity	0.491229595527877	bayes_pls_golite062009
protein binding	0.110986062813054	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: