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View Structure Prediction Details

Protein: NAT10_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 1056 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAT10_YEAST.

Description E-value Query
Range
Subject
Range
gi|10433597, gi|... - gi|13399322|ref|NP_078938.1| N-acetyltransferase 10 [Homo sapiens], gi|10433597|dbj|BAB13995.1| unna...
0.0 [1..1056] [1..1010]
U202B_ARATH, U20... - (Q9M2Q4) Hypothetical UPF0202 protein At3g57940, UPF0202 protein At3g57940 - Arabidopsis thaliana (M...
0.0 [3..1006] [2..971]
NAT10_SCHPO - RNA cytidine acetyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nat10 PE=1 ...
SPAC20G8.09c - N-acetyltransferase Nat10
0.0 [1..1053] [1..1030]
CE11131 - status:Partially_confirmed UniProt:O01757 protein_id:AAB54126.1
0.0 [3..1041] [2..1025]
NAT10_YEAST - RNA cytidine acetyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAT10 PE=...
KRE33 - Essential protein, required for biogenesis of the small ribosomal subunit; heterozygous mutant shows...
0.0 [1..1056] [1..1056]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKAIDSRI PSLIRNGVQT KQRSIFVIVG DRARNQLPNL HYLMMSADLK MNKSVLWAYK  60
   61 KKLLGFTSHR KKRENKIKKE IKRGTREVNE MDPFESFISN Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.527 d.68.3 SirA-like
View Download 0.410 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.513 c.5.1 MurCD N-terminal domain
View Download 0.474 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.403 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.402 b.1.1 Immunoglobulin
View Download 0.386 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.358 c.78.1 Aspartate/ornithine carbamoyltransferase
View Download 0.349 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.340 c.47.1 Thioredoxin-like
View Download 0.313 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.295 c.3.1 FAD/NAD(P)-binding domain
View Download 0.279 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.275 c.54.1 IIA domain of mannose transporter, IIA-Man
View Download 0.258 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.254 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.253 d.68.7 R3H domain
View Download 0.253 c.30.1 PreATP-grasp domain
View Download 0.245 c.23.8 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
View Download 0.243 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.229 a.118.8 TPR-like
View Download 0.224 c.114.1 YchN-like
View Download 0.216 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.211 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [102-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIRYVYYKES EKILGNTYGM CILQDFEALT PNLLARTIET VEGGGIVVIL LKSMSSLKQL  60
   61 YTMTMDVHAR YRTEAHGDVV ARFNERFILS LGSNPNCLVV DDELNVLPLS GAKNVKPLPP 120
  121 KEDDELPPKQ LELQELKESL EDVQPAGSLV SLSKTVNQAH AILSFIDAIS EKTLNFTVAL 180
  181 TAGRGRGKSA ALGISIAAAV SHGYSNIFVT SPSPENLKTL FEFIFKGFDA LGYQEHIDYD 240
  241 IIQSTNPDFN KAIVRVDIKR DHRQTIQYIV PQDHQVLGQA ELVVIDEAAA IPLPIVKNLL 300
  301 GPYLVFMAST INGYEGTGRS LSLKLIQQLR NQNNTSGRES TQTAVVSRDN KEKDSHLHSQ 360
  361 SRQLREISLD EPIRYAPGDP IEKWLNKLLC LDVTLIKNPR FATRGTPHPS QCNLFVVNRD 420
  421 TLFSYHPVSE NFLEKMMALY VSSHYKNSPN DLQLMSDAPA HKLFVLLPPI DPKDGGRIPD 480
  481 PLCVIQIALE GEISKESVRN SLSRGQRAGG DLIPWLISQQ FQDEEFASLS GARIVRIATN 540
  541 PEYASMGYGS RAIELLRDYF EGKFTDMSED VRPKDYSIKR VSDKELAKTN LLKDDVKLRD 600
  601 AKTLPPLLLK LSEQPPHYL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [721-814]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HYLGVSYGLT QSLHKFWKNN SFVPVYLRQT ANDLTGEHTC VMLNVLEGRE SNWLVEFAKD  60
   61 FRKRFLSLLS YDFHKFTAVQ ALSVIESSKK AQDL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.754 0.078 nucleolus d.80.1 Tautomerase/MIF
View Download 0.747 0.021 nucleolus d.52.7 Ribosome-binding factor A, RbfA
View Download 0.503 0.014 nucleolus a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.469 N/A N/A b.40.2 Bacterial enterotoxins
View Download 0.438 N/A N/A d.67.2 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
View Download 0.409 N/A N/A b.36.1 PDZ domain-like
View Download 0.398 N/A N/A d.15.1 Ubiquitin-like
View Download 0.397 N/A N/A b.84.2 Rudiment single hybrid motif
View Download 0.393 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.382 N/A N/A d.93.1 SH2 domain
View Download 0.382 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.381 N/A N/A d.58.5 GlnB-like
View Download 0.378 N/A N/A a.64.1 Saposin
View Download 0.368 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.367 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.366 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.365 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.364 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.359 N/A N/A c.55.4 Translational machinery components
View Download 0.348 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.336 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.335 N/A N/A a.29.2 Bromodomain
View Download 0.335 N/A N/A a.112.1 Description not found.
View Download 0.334 N/A N/A b.40.2 Bacterial enterotoxins
View Download 0.315 N/A N/A d.64.1 eIF1-like
View Download 0.314 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.311 N/A N/A d.21.1 Diaminopimelate epimerase-like
View Download 0.304 N/A N/A d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.303 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.295 N/A N/A a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.295 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.287 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.287 N/A N/A d.58.19 Bacterial exopeptidase dimerisation domain
View Download 0.283 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.283 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.279 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.278 N/A N/A d.27.1 Ribosomal protein S16
View Download 0.276 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.272 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.253 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.246 N/A N/A a.64.1 Saposin
View Download 0.245 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.243 N/A N/A d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.241 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.240 N/A N/A d.20.1 UBC-like
View Download 0.229 N/A N/A d.52.6 BolA-like
View Download 0.227 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.226 N/A N/A d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.225 N/A N/A a.118.8 TPR-like
View Download 0.222 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.222 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.211 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.205 N/A N/A c.23.1 CheY-like

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 2.58352785213483 bayes_pls_golite062009
binding 2.3830857772509 bayes_pls_golite062009
structural molecule activity 1.70306030734033 bayes_pls_golite062009
RNA helicase activity 1.40594009629203 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.38650114394757 bayes_pls_golite062009
RNA-dependent ATPase activity 1.372924601535 bayes_pls_golite062009
helicase activity 1.17712281740941 bayes_pls_golite062009
ATP-dependent helicase activity 1.12969667337016 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.12969667337016 bayes_pls_golite062009
RNA binding 0.90930722867621 bayes_pls_golite062009
nucleic acid binding 0.61841039337932 bayes_pls_golite062009
0.506052368661833 bayes_pls_golite062009
DNA binding 0.327221599656875 bayes_pls_golite062009
transcription regulator activity 0.179080000736404 bayes_pls_golite062009
protein binding 0.102043618157662 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0283323446458181 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [815-1056]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDDEKHDNKE LTRTHLDDIF SPFDLKRLDS YSNNLLDYHV IGDMIPMLAL LYFGDKMGDS  60
   61 VKLSSVQSAI LLAIGLQRKN IDTIAKELNL PSNQTIAMFA KIMRKMSQYF RQLLSQSIEE 120
  121 TLPNIKDDAI AEMDGEEIKN YNAAEALDQM EEDLEEAGSE AVQAMREKQK ELINSLNLDK 180
  181 YAINDNSEEW AESQKSLEIA AKAKGVVSLK TGKKRTTEKA EDIYRQEMKA MKKPRKSKKA 240
  241 AN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle