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View Structure Prediction Details

Protein: PID2_ARATH
Organism: Arabidopsis thaliana
Length: 525 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PID2_ARATH.

Description E-value Query
Range
Subject
Range
gi|110738299 - gi|110738299|dbj|BAF01078.1| putative second messenger-dependent protein kinase [Arabidopsis thalian...
345.0 [0..1] [525..50]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSSIFYKD NESDYESSTV GPDSSRRTSW LSSSFTASPS CSSISHLSNH GLNSYNQSKP  60
   61 HKANQVAWEA MARLRRCCGR AV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 2ptkA
Description: CHICKEN SRC TYROSINE KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.06905798270146 bayes_pls_golite062009
protein binding 2.08632303609243 bayes_pls_golite062009
cytoskeletal protein binding 0.83493091348808 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [83-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLEHFRLLKR LGSGDIGSVY LCQIRGSPET AFYAMKVVDK EAVAVKKKLG RAEMEKKILG  60
   61 MLDHPFCPTL YAAFEASHYS FLVMEYCPGG DLYAVRLRQP SKRFTISSTR FYAAETLVAL 120
  121 EYLHMMGIVY RDLKPENVLI REDGHVMLSD FDLSFKCDVV PQFLSDNDRD RGHQEDDDDI 180
  181 SIRRKCSTPS CTTTPLNPVI SCFSPTSSRR RKKNVVTTTI HENAAGTSDS VKSNDVSRTF 240
  241 SRSPSSCSRV SNGLRDISGG CPSIFAEPIN ARSKSFVGTH EYLAPEVISG QGHGSAVDWW 300
  301 TYGIFLYEMI FGRTPFK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.30103
Match: 1mrvA
Description: crystal structure of an inactive Akt2 kinase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 5.4586557943719 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.04467222534257 bayes_pls_golite062009
kinase activity 4.85903980916957 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.63692708178478 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.26787750561728 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
MAP kinase activity 0.81943579965027 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [400-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDNNEKTLVN ILKAPLTFPK VIVNSPKEYE DMVNAQDLII KLLVKNPKKR LGSLKGSIEI  60
   61 KRHEFFEGVN WALIRSIKPP WVPKEETSHK TKGDNRSVNY YLPPRFMMSR KERNEPYHVS 120
  121 NYFDYF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.2
Match: 2jdoA
Description: No description for 2jdoA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle