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View Structure Prediction Details

Protein: asd-2
Organism: Caenorhabditis elegans
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asd-2.

Description E-value Query
Range
Subject
Range
asd-2 - status:Confirmed UniProt:Q7Z153 protein_id:AAP68907.1
303.0 [0..53] [445..11]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDCDNGVVSE ISDDKELLNL ETVIPPPPND SGHEFIGPSS GPPQVTITPS GVQSGSANGV  60
   61 STSQQQQYSA EYLSQLLKDK KQLAAFPNVF HHLERLADEE INKVRVVLFQ CE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSKESAPLPD AEGDSTVHTE KVFVPAKEHP DYNFVGRILG PRGMTAKQLE QETGCKIMVR  60
   61 GRGSMRDKKK EELNRGKPNW EHLSEELHVL IQCEDTENRA KVKLMRAVEE VRKLLVPAPE 120
  121 GEDDLKRKQL MELAIINGTY RSGTDQSALA A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 2bl5A
Description: Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.79066340213332 bayes_pls_golite062009
nucleic acid binding 3.1702329067388 bayes_pls_golite062009
mRNA binding 2.45375256113953 bayes_pls_golite062009
binding 2.12000404411947 bayes_pls_golite062009
transcription regulator activity 0.720255318931267 bayes_pls_golite062009
catalytic activity 0.483552478758071 bayes_pls_golite062009
protein binding 0.446932489882167 bayes_pls_golite062009
DNA binding 0.369815489813612 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [264-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQLAAVKHQQ QPFAAALQAA ALQRGVLPMM ANGLSRSPTM AVCGAPIVMS PSGRASSAGA  60
   61 TATSQAALIM QQQSQLHAAN AGNAALQQQA ALLQQQQAAE YQQLLLSQAG LYDFSAMQQQ 120
  121 YAAVGQNAAV AAAQAQAQAQ YGALAAAAAA NSAGNQQYAD YAGVDLTSQQ SAHGGYYVRR 180
  181 WA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle