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View Structure Prediction Details

Protein: asd-2
Organism: Caenorhabditis elegans
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asd-2.

Description E-value Query
Range
Subject
Range
asd-2 - status:Confirmed UniProt:Q7Z153 protein_id:AAP68907.1
303.0 [0..53] [445..11]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDCDNGVVSE ISDDKELLNL ETVIPPPPND SGHEFIGPSS GPPQVTITPS GVQSGSANGV  60
   61 STSQQQQYSA EYLSQLLKDK KQLAAFPNVF HHLERLADEE INKVRVVLFQ CE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSKESAPLPD AEGDSTVHTE KVFVPAKEHP DYNFVGRILG PRGMTAKQLE QETGCKIMVR  60
   61 GRGSMRDKKK EELNRGKPNW EHLSEELHVL IQCEDTENRA KVKLMRAVEE VRKLLVPAPE 120
  121 GEDDLKRKQL MELAIINGTY RSGTDQSALA A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 2bl5A
Description: Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.79066340213332 bayes_pls_golite062009
nucleic acid binding 3.1702329067388 bayes_pls_golite062009
mRNA binding 2.45375256113953 bayes_pls_golite062009
binding 2.12000404411947 bayes_pls_golite062009
transcription regulator activity 0.720255318931267 bayes_pls_golite062009
catalytic activity 0.483552478758071 bayes_pls_golite062009
protein binding 0.446932489882167 bayes_pls_golite062009
DNA binding 0.369815489813612 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [264-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQLAAVKHQQ QPFAAALQAA ALQRGVLPMM ANGLSRSPTM AVCGAPIVMS PSGRASSAGA  60
   61 TATSQAALIM QQQSQLHAAN AGNAALQQQA ALLQQQQAAE YQQLLLSQAG LYDFSAMQQQ 120
  121 YAAVGQNAAV AAAQAQAQAQ YGALAAAAAA NSAGNQQYAD YAGVDLTSQQ SAHGGYYVRR 180
  181 WA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle