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View Structure Prediction Details

Protein: ENSPTRT00000028219
Organism: Pan troglodytes
Length: 389 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENSPTRT00000028219.

Description E-value Query
Range
Subject
Range
gi|114587651 - gi|114587651|ref|XP_520898.2| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 ...
1.0E-88 [1..389] [219..628]
gi|149040032, gi... - gi|38454206|ref|NP_942025.1| proteasome, 26S, non-ATPase regulatory subunit 6 [Rattus norvegicus], g...
5.0E-85 [1..389] [1..389]
gi|109037701 - gi|109037701|ref|XP_001093028.1| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase,...
gi|90074922 - gi|90074922|dbj|BAE87141.1| unnamed protein product [Macaca fascicularis]
8.0E-85 [1..389] [1..389]
PSMD6_MOUSE - 26S proteasome non-ATPase regulatory subunit 6 OS=Mus musculus GN=Psmd6 PE=1 SV=1
9.0E-85 [1..389] [1..389]
PSMD6_BOVIN - 26S proteasome non-ATPase regulatory subunit 6 OS=Bos taurus GN=PSMD6 PE=2 SV=1
2.0E-84 [1..389] [1..389]
gi|73985103 - gi|73985103|ref|XP_541816.2| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 6 (2...
2.0E-84 [1..389] [1..389]
gi|27694784, gi|... - gi|27694784|gb|AAH43825.1| P44s10-prov protein [Xenopus laevis], gi|147904380|ref|NP_001080462.1| hy...
4.0E-84 [1..389] [1..389]
gi|89268727, gi|... - gi|89268727|emb|CAJ83374.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [Xenopus trop...
9.0E-84 [1..389] [1..389]

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Predicted Domain #1
Region A:
Residues: [1-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLENLEEEG LPKNPDLRIA QLRFLLSLPE HRGDAAVRDE LMAAVRDNNM APYYEALCKS  60
   61 LDWQIDVDLL NKMKKANEDE LKRLDEELED AEKNLGESEI RDAMMAKAEY LCRIGDKEGA 120
  121 LTAFRKTYDK TVALGHRLDI VFYLLRIGLF YMDNDLITRN TEKAKSLIEE GGDWDRRNRL 180
  181 KVYQGLYCVA IRDFKQAAEL FLDTVSTFTS YELMDYKTFV TYTVYVSMIA LERPDLREKV 240
  241 IKGAEILEVL HSLPAVRQYL FSLYECRYSV FFQSLAVVEQ EMKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.47
Match: 2ifuA
Description: No description for 2ifuA was found.

Predicted Domain #2
Region A:
Residues: [285-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DWLFAPHYRY YVREMRIHAY SQLLESYRSL TLGYMAEAFG VGVEFIDQEL SRFIAAGRLH  60
   61 CKIDKVNEIV ETNRPDSKNW QYQETIKKGD LLLNRVQKLS RVINM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.154902
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.50995556050336 bayes_pls_golite062009
nucleic acid binding 3.38144578566524 bayes_pls_golite062009
binding 3.33026160538031 bayes_pls_golite062009
DNA binding 3.30822066787723 bayes_pls_golite062009
transcription factor activity 2.60537570879007 bayes_pls_golite062009
hydrolase activity 2.30467124306022 bayes_pls_golite062009
sequence-specific DNA binding 1.32971938164691 bayes_pls_golite062009
transcription activator activity 1.08566311616647 bayes_pls_golite062009
transcription repressor activity 0.95491822926452 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.505349137311395 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.42135864069093 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.136726704233672 bayes_pls_golite062009
small conjugating protein ligase activity 0.118016217031359 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle