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View Structure Prediction Details

Protein: ENSPTRT00000005590
Organism: Pan troglodytes
Length: 623 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENSPTRT00000005590.

Description E-value Query
Range
Subject
Range
gi|148669738, gi... - gi|74204048|dbj|BAE29019.1| unnamed protein product [Mus musculus], gi|148669738|gb|EDL01685.1| X-pr...
0.0 [1..623] [44..666]
XPP1_RAT - Xaa-Pro aminopeptidase 1 OS=Rattus norvegicus GN=Xpnpep1 PE=1 SV=1
0.0 [1..623] [1..623]
gi|2584787, gi|9... - gi|9739017|gb|AAF97866.1|AF195530_1 soluble aminopeptidase P [Homo sapiens], gi|2584787|emb|CAA65068...
0.0 [1..623] [1..623]
gi|73998513 - gi|73998513|ref|XP_544010.2| PREDICTED: similar to X-prolyl aminopeptidase (aminopeptidase P) 1, sol...
0.0 [1..623] [1..623]
XPP1_BOVIN - Xaa-Pro aminopeptidase 1 OS=Bos taurus GN=XPNPEP1 PE=2 SV=1
0.0 [1..622] [1..622]
gi|148725981, gi... - gi|47085707|ref|NP_998145.1| X-prolyl aminopeptidase (aminopeptidase P) 1, soluble [Danio rerio], gi...
0.0 [1..619] [1..619]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPKVTSELL RQLRQAMRNS EYVTEPIQAY IIPSGDAHQS EYIAPCDCRR AFVSGFDGSA  60
   61 GTAIITEEHA AMWTDGRYFL QAAKQMDSNW TLMKMGLKDT PTQEDWLVSV LPEGSRVGVD 120
  121 PLIIPTDYWK KMAKVLRSAG HHLIPVKENL VDKIWTDRPE RPCKPLLTLG LD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.11
Match: 1chmA
Description: Creatinase; Creatinase, catalytic (C-terminal) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [173-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTGISWKDKV ADLRLKMAER NVMWFVVTAL DEIAWLFNLR GSDVEHNPVF FSYAIIGLET  60
   61 IMLFIDGDRI DAPSVKEHLL LDLGLEAEYR IQVHPYKSIL SELKALCADL SPREKVWVSD 120
  121 KASYAVSETI PKDHRCCMPY TPICIAKAVK NSAESEGMRR AHIKDAVALC ELFNWLEKEV 180
  181 PKGGVTEISA ADKAEEFRRQ QADFVDLSFP TISSTGPNGA IIHYAPVPET NRTLSLDEVY 240
  241 LIDSGAQYKD GTTDVTRTMH FGTPTAYEKE CFTYVLKGHI AVSAAVFPTG TKGHLLDSFA 300
  301 RSALWDSGLD YLHGTGHGVG SFLNVHEGPC GISYKTFSDE PLEAGMIVTD EPGYYEDGAF 360
  361 GIRIENVVLV VPVKTKYNFN NRGSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 1pv9A
Description: Prolidase from Pyrococcus furiosus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.60615909541559 bayes_pls_golite062009
transcription regulator activity 2.3228898238998 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.18503136472662 bayes_pls_golite062009
nucleic acid binding 2.09388149606759 bayes_pls_golite062009
DNA binding 1.92799814679615 bayes_pls_golite062009
binding 1.4562583231987 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
transcription factor activity 1.22693836163332 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
exopeptidase activity 0.762255574851485 bayes_pls_golite062009
metallopeptidase activity 0.629480947971878 bayes_pls_golite062009
protein binding 0.170797254754318 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [558-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFEPLTLVPI QTKMIDVDSL TDKECDWLNN YHLTCRDVIG KELQKQGRQE ALEWLIRETQ  60
   61 PISKQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.30103
Match: 1b59A
Description: Methionine aminopeptidase, insert domain; Methionine aminopeptidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.60615909541559 bayes_pls_golite062009
transcription regulator activity 2.3228898238998 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.18503136472662 bayes_pls_golite062009
nucleic acid binding 2.09388149606759 bayes_pls_golite062009
DNA binding 1.92799814679615 bayes_pls_golite062009
binding 1.4562583231987 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
transcription factor activity 1.22693836163332 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
exopeptidase activity 0.762255574851485 bayes_pls_golite062009
metallopeptidase activity 0.629480947971878 bayes_pls_golite062009
protein binding 0.170797254754318 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009

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