YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|17427796
Organism:	Ralstonia solanacearum
Length:	117 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17427796.

Description	E-value	Query Range	Subject Range
gi\|118649112, gi... - gi\|118713573\|ref\|ZP_01566138.1\| Peptidylprolyl isomerase [Burkholderia cenocepacia MC0-3], gi\|118649... gi\|67656803, gi\|... - gi\|67656803\|ref\|ZP_00454184.1\| Peptidylprolyl isomerase [Burkholderia cenocepacia AU 1054], gi\|67095... gi\|67667692, gi\|... - gi\|67667692\|ref\|ZP_00464906.1\| Peptidylprolyl isomerase [Burkholderia cenocepacia HI2424], gi\|670987...	174.0	[0..1]	[117..107]
gi\|22294826, gi\|... - gi\|22298646\|ref\|NP_681893.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Thermosynechococcus elon...	159.0	[0..3]	[117..51]
gi\|56751758, gi\|... - gi\|56751758\|ref\|YP_172459.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Synechococcus elongatus ... gi\|81301163, gi\|... - gi\|81301163\|ref\|YP_401371.1\| peptidylprolyl isomerase [Synechococcus elongatus PCC 7942], gi\|8117004...	158.0	[0..3]	[117..62]
gi\|116073364, gi... - gi\|116073364\|ref\|ZP_01470626.1\| FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) [Synechococcu...	157.0	[0..4]	[117..95]
gi\|87125507, gi\|... - gi\|87125507\|ref\|ZP_01081352.1\| Peptidylprolyl isomerase [Synechococcus sp. RS9917], gi\|86166807\|gb\|E...	156.0	[0..1]	[117..99]
gi\|85697575, gi\|... - gi\|85715636\|ref\|ZP_01046616.1\| peptidylprolyl isomerase, FKBP-type [Nitrobacter sp. Nb-311A], gi\|856...	155.0	[0..5]	[117..51]
gi\|78063108, gi\|... - gi\|78063108\|ref\|YP_373016.1\| peptidylprolyl isomerase [Burkholderia sp. 383], gi\|77970993\|gb\|ABB1237...	155.0	[0..1]	[117..1]
gi\|74015026, gi\|... - gi\|74015026\|ref\|ZP_00685654.1\| Peptidylprolyl isomerase [Burkholderia ambifaria AMMD], gi\|72611829\|g... gi\|170701910, gi... - gi\|170701910\|ref\|ZP_02892836.1\| peptidylprolyl isomerase FKBP-type [Burkholderia ambifaria IOP40-10]... gi\|118695729, gi... - gi\|172062768\|ref\|YP_001810419.1\| peptidylprolyl isomerase FKBP-type [Burkholderia ambifaria MC40-6],...	155.0	[0..1]	[117..1]
gi\|88787084, gi\|... - gi\|88809142\|ref\|ZP_01124651.1\| Peptidylprolyl isomerase [Synechococcus sp. WH 7805], gi\|88787084\|gb\|...	155.0	[0..4]	[117..90]
gi\|255666158, gi... - gi\|83716167\|ref\|YP_438754.1\| FK506-binding protein [Burkholderia thailandensis E264], gi\|83649992\|gb... gi\|167615273 - gi\|167615273\|ref\|ZP_02383908.1\| FK506-binding protein [Burkholderia thailandensis Bt4] gi\|167577103 - gi\|167577103\|ref\|ZP_02369977.1\| FK506-binding protein [Burkholderia thailandensis TXDOH]	155.0	[0..1]	[117..1]

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Predicted Domain #1

Region A:
Residues: [1-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTITTTQSGL QYEDVTVGDG AEATAGKYVT VHYTGWLYEN GQAGRKFDSS KDRNDPFAFP  60
   61 LGAGHVIKGW DEGVQGMKVG GTRKLIIPAE LGYGARGAGG VIPPNATLLF EVDLLEV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.045757
Match:	1fkkA
Description:	ATOMIC STRUCTURE OF FKBP12, AN IMMUNOPHILIN BINDING PROTEIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ryanodine-sensitive calcium-release channel activity	10.9968443145942	bayes_pls_golite062009
intracellular ligand-gated calcium channel activity	10.9968443145942	bayes_pls_golite062009
macrolide binding	7.31599503004442	bayes_pls_golite062009
FK506 binding	7.22442625476031	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.74926751944787	bayes_pls_golite062009
calcium channel activity	6.4374377859142	bayes_pls_golite062009
cation channel activity	6.06732269872248	bayes_pls_golite062009
ion channel activity	5.45007096522107	bayes_pls_golite062009
passive transmembrane transporter activity	5.32426176964634	bayes_pls_golite062009
channel activity	5.32426176964634	bayes_pls_golite062009
substrate-specific channel activity	5.28960420749143	bayes_pls_golite062009
gated channel activity	5.28074654906904	bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity	4.0615867467963	bayes_pls_golite062009
cis-trans isomerase activity	3.99265212272703	bayes_pls_golite062009
ligand-gated channel activity	3.34717828007833	bayes_pls_golite062009
ligand-gated ion channel activity	3.34717828007833	bayes_pls_golite062009
ion transmembrane transporter activity	2.6566793500337	bayes_pls_golite062009
cation transmembrane transporter activity	2.61794461605199	bayes_pls_golite062009
calcium-release channel activity	2.58969194870156	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.47257819150887	bayes_pls_golite062009
isomerase activity	2.31710030777753	bayes_pls_golite062009
transcription regulator activity	1.85589011277711	bayes_pls_golite062009
receptor activity	1.78361575899771	bayes_pls_golite062009
transmembrane receptor activity	1.7459556028988	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.68688812199737	bayes_pls_golite062009
kinase activity	1.67904764195462	bayes_pls_golite062009
binding	1.63170667962375	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.57898291235576	bayes_pls_golite062009
signal transducer activity	1.53711974553033	bayes_pls_golite062009
molecular transducer activity	1.53711974553033	bayes_pls_golite062009
protein kinase activity	1.45320632553313	bayes_pls_golite062009
drug binding	1.39643621593407	bayes_pls_golite062009
transferase activity	1.34122735969662	bayes_pls_golite062009
receptor serine/threonine kinase binding	1.32709321745178	bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding	1.32470025150272	bayes_pls_golite062009
transforming growth factor beta receptor binding	1.32470025150272	bayes_pls_golite062009
transporter activity	1.25197125648774	bayes_pls_golite062009
protein binding	1.08765413491791	bayes_pls_golite062009
SMAD binding	1.04905381164355	bayes_pls_golite062009
transmembrane transporter activity	1.03909235910355	bayes_pls_golite062009
catalytic activity	0.885282592863018	bayes_pls_golite062009
substrate-specific transporter activity	0.789390402522536	bayes_pls_golite062009
transmembrane receptor protein kinase activity	0.780499202755666	bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase activity	0.763739321802433	bayes_pls_golite062009
transforming growth factor beta receptor activity	0.763739321802433	bayes_pls_golite062009
intracellular ligand-gated ion channel activity	0.727019445105701	bayes_pls_golite062009
protein serine/threonine kinase activity	0.671059013500415	bayes_pls_golite062009
activin binding	0.33489895389042	bayes_pls_golite062009
unfolded protein binding	0.27473817613726	bayes_pls_golite062009
histone binding	0.221748741603068	bayes_pls_golite062009
transcription elongation regulator activity	0.21145105012677	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: