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View Structure Prediction Details

Protein: MNS2_ARATH
Organism: Arabidopsis thaliana
Length: 572 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNS2_ARATH.

Description E-value Query
Range
Subject
Range
gi|15292685 - gi|15292685|gb|AAK92711.1| putative mannosidase [Arabidopsis thaliana]
768.0 [0..1] [572..1]

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Predicted Domain #1
Region A:
Residues: [1-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARNKLVSGS HGIWKYFNPA FYLRRPRRLA LLIILFVSVS MVVWDRQSLS RDYQFEVSKL  60
   61 NEEVLRLQQM LEEIKSVTED VSVNSLKDVQ EDPVDAQRMQ RVKEAMVHAW SSYEKYAWGQ 120
  121 DELQPQTKDG VDSFGGLGAT MIDALDTLYI MGLDEQFQKA REWVASSLDF DKDYAASMFE 180
  181 TTIRVVGGLL SAYDLSGDKI FLEKAMDIAD RLLPAWDTQS GIPYNIINLK HGNAHNPTWA 240
  241 GGDSILADSG TEQLEFIALS QRTGDPKYQQ KVEKVISVLN KNFPADGLLP IYINPDTANP 300
  301 SQSTITFGAM GDSFYEYLLK VWVFGNKTSA VKHYRDMWEK SMNGLLSLVK KSTPLSFTYI 360
  361 CEKSGNSLID KMDELACFAP GMLALGASGY SDPAEGKKFL TLAEELAWTC YNFYQSTPTK 420
  421 LAGENYFFNS GSDMSVGTSW NILRPETVES LFYLWRLTGN KTYQEWGWNI FEAFEKNSRI 480
  481 ESGYVGLKDV NTGVKDNKMQ SFFLAETLKY LYLLFSPTTV IPLDEWVFNT EAHPLKIKSR 540
  541 NDQVNLKQSN KVLLRKPAFR IRQRHYGRIT KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.0
Match: 1nxcA
Description: Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide mannosidase activity 7.089685350864 bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 6.95179264736435 bayes_pls_golite062009
mannosidase activity 5.20286438265852 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.31319275372149 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.65589746311782 bayes_pls_golite062009
hydrolase activity 2.67964748309919 bayes_pls_golite062009
binding 1.49199031708525 bayes_pls_golite062009
catalytic activity 1.31873306707813 bayes_pls_golite062009
cation binding 0.362242764130218 bayes_pls_golite062009
metal ion binding 0.362242764130218 bayes_pls_golite062009
protein binding 0.36081692928767 bayes_pls_golite062009
ion binding 0.355220167272296 bayes_pls_golite062009
calcium ion binding 0.121126738064555 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle