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View Structure Prediction Details

Protein: ANGI_RHIAV
Organism: Rhinopithecus avunculus
Length: 146 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ANGI_RHIAV.

Description E-value Query
Range		 Subject
Range
ANGI_TRAFR - Angiogenin OS=Trachypithecus francoisi GN=ANG PE=3 SV=1
 221.0 [0..1] [146..1]
ANGI_MIOTA - Angiogenin OS=Miopithecus talapoin GN=ANG PE=3 SV=1
 219.0 [0..1] [146..1]
ANGI_CHLAE - Angiogenin OS=Chlorocebus aethiops GN=ANG PE=3 SV=1
 214.0 [0..1] [146..1]
ANGI_PONPY - Angiogenin OS=Pongo pygmaeus GN=ANG PE=3 SV=1
 213.0 [0..1] [145..1]
ANGI_MACMU - Angiogenin OS=Macaca mulatta GN=ANG PE=3 SV=1
 212.0 [0..1] [146..1]
gi|26344600, gi|... - gi|31981520|ref|NP_035401.2| pancreatic ribonuclease [Mus musculus], gi|26344600|dbj|BAC35949.1| unn...
 210.0 [0..3] [143..1]
ANGI_SAGOE - Angiogenin OS=Saguinus oedipus GN=ANG PE=3 SV=1
 209.0 [0..1] [146..1]
RNS1A_RATEX - Ribonuclease pancreatic alpha-type OS=Rattus exulans PE=3 SV=1
 209.0 [0..3] [143..1]
RNAS1_MUSSA - Ribonuclease pancreatic OS=Mus saxicola GN=Rnase1 PE=2 SV=1
 209.0 [0..3] [143..1]
gi|55742836, gi|... - gi|55742836|ref|NP_001006993.1| angiogenin, ribonuclease A family, member 1 [Rattus norvegicus], gi|...
gi|55742836 - ref|NP_001006993.1| angiogenin, ribonuclease A family, member 1 [Rattus norvegicus]
 206.0 [0..1] [145..1]

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Predicted Domain #1
Region A:
Residues: [1-146] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMGLGLFLL VFMLGLGLTP PTLAQDNSRY RDFLTKHYDA TPQGRNDRYC ESMMRRRGLT  60
   61 SPCKDINTFI HGNSRHIKAI CGDENGNPYG ENLRISKSPF QVTTCNLRGG SSRPPCRYRA 120
  121 TAGFRNIVVA CENDLPVHLD QSIFRP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 1gv7A
Description: Angiogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
copper ion binding 7.83873950118271 bayes_pls_golite062009
ribonuclease activity 7.7836205160091 bayes_pls_golite062009
glycosaminoglycan binding 5.76187095683544 bayes_pls_golite062009
heparin binding 5.47129826629317 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.17394108203326 bayes_pls_golite062009
polysaccharide binding 5.05032546822599 bayes_pls_golite062009
actin binding 4.92941980452441 bayes_pls_golite062009
cytoskeletal protein binding 4.36902055736911 bayes_pls_golite062009
receptor binding 3.75411703515817 bayes_pls_golite062009
pattern binding 3.51086739633778 bayes_pls_golite062009
nuclease activity 3.07697924678131 bayes_pls_golite062009
carbohydrate binding 2.53927247892334 bayes_pls_golite062009
binding 2.456168052491 bayes_pls_golite062009
protein binding 2.18342402068792 bayes_pls_golite062009
nucleic acid binding 2.03519718891127 bayes_pls_golite062009
hydrolase activity 1.87908884191558 bayes_pls_golite062009
DNA binding 1.74627208866206 bayes_pls_golite062009
catalytic activity 1.25983854650131 bayes_pls_golite062009
transition metal ion binding 1.13983199214716 bayes_pls_golite062009
ion binding 0.595243569666936 bayes_pls_golite062009
cation binding 0.579280414941568 bayes_pls_golite062009
metal ion binding 0.579280414941568 bayes_pls_golite062009
RNA binding 0.13382390101771 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle