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View Structure Prediction Details

Protein: MRG1_ARATH
Organism: Arabidopsis thaliana
Length: 320 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRG1_ARATH.

Description E-value Query
Range
Subject
Range
gi|94406757 - gi|94406757|ref|XP_981969.1| PREDICTED: similar to mortality factor 4 like 1 isoform b [Mus musculus...
318.0 [0..22] [315..4]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSSKEETA SDGDTASGGA SPSNDGRLFS EGERVLAYHG PRVYGAKVQK VELRKKEWKY  60
   61 FVHYLGWNKN WDEWVSADRL LKHTEENLVK QKALDKKQGV EKGTKSGRSA QTKTRSSADT 120
  121 KADK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 2efiA
Description: No description for 2efiA was found.

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
chromatin binding 3.84065302930105 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
protein binding 1.61683263008775 bayes_pls_golite062009
satellite DNA binding 1.4681464542396 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009
transcription activator activity 0.136090220479238 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [125-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDTKTNAAKG KKRKHESGNE KDNVTAEKLM KIQIPASLKK QLTDDWEYIA QKDKVVKLPR  60
   61 SPNVDEILSK YLEFKTKKDG MVTDSVAEIL KGIRSYFDKA LPVMLLYKKE RRQYQESIVD 120
  121 DTSPSTVYGA EHLLRLFVKL PDLFSYVNME EETWSRMQQT LSDFLKFIQK NQSTFLLPSA 180
  181 YDSDKVSDGK GKGKDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.69897
Match: 2aqlA
Description: Crystal Structure of the MRG15 MRG domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle