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View Structure Prediction Details

Protein: Vmat-PE, Vmat-PC...
Organism: Drosophila melanogaster
Length: 610 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Vmat-PE, Vmat-PC....

Description E-value Query
Range
Subject
Range
gi|25012572 - gi|25012572|gb|AAN71386.1| RE38567p [Drosophila melanogaster]
368.0 [0..1] [610..1]

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Predicted Domain #1
Region A:
Residues: [1-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSSTDAGNG GPRKHTQSTA PQKQSEISET TSFTVNANTT TNSQQQQIPG GPASNTPSKN  60
   61 PFKQQLDSNQ QNGNMEPDCG IMGVGKEPPV PPPPTYQSQT YAGRQAPPPA DQYREEDPRA 120
  121 AGSWAAAKSW MVSWRGSNRL VLVIVAIALL LDNMLLTTVV PIIPEFLYDI RHPDAPLDSF 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [181-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRTPLTSNVP PPPTPCPCNK DGSEAAPLEI STISPEENET YYRELEERHN ELVGETVEVG  60
   61 LLFASKAFVQ LLVNPIVGPL THRIGYSIPM FAGFVIMFLS TIIFAFGRSY LVLFVARALQ 120
  121 GIGSSCSSVS GMGMLADRFT DDKERGNAMG IALGGLALGV LIGPPFGGVM YEFVGKSAPF 180
  181 LILAALALGD GLLQLFMLQP SIQKAETEPP SLKSLISDPY ILIAAGAITF ANMGIAMLEP 240
  241 SLPLWMVDNM GATRWEQGVA FLPASISYLI GTNLFGPLGH KIGRWFAACL GLIIIGGCLI 300
  301 FIPMATSITH LIIPNAGLGF AIGMVDSSMM PELGYLVDIR HSAVYGSVYA LGDVAFCVGF 360
  361 AVGPALSGSL VKSIGFEWML FGIAILCFMY APLLTLLKNP PTSDEKKSLI YGRDRAQVRY 420
  421 VTYQNYEEDE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.09691
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.24937104052238 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
binding 1.05701989682533 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle