YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|195632230, gi...
Organism:	Salmonella enterica subsp. enterica serovar Newport str. SL317
Length:	213 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|195632230, gi....

Description	E-value	Query Range	Subject Range
PYRE_SHISS - Orotate phosphoribosyltransferase OS=Shigella sonnei (strain Ss046) GN=pyrE PE=3 SV=1	207.0	[0..1]	[213..1]
PYRE_VIBCH - Orotate phosphoribosyltransferase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N... gi\|254847045, gi... - gi\|254851340\|ref\|ZP_05240690.1\| orotate phosphoribosyltransferase [Vibrio cholerae MO10], gi\|2548470... PYRE_VIBCH - Orotate phosphoribosyltransferase OS=Vibrio cholerae GN=pyrE PE=1 SV=2	206.0	[0..1]	[213..1]
gi\|254038842, gi... - gi\|254038842\|ref\|ZP_04872894.1\| orotate phosphoribosyltransferase [Escherichia sp. 1_1_43], gi\|22683... gi\|227883810, gi... - gi\|227883810\|ref\|ZP_04001615.1\| orotate phosphoribosyltransferase [Escherichia coli 83972], gi\|22783... gi\|26110718, gi\|... - gi\|26250288\|ref\|NP_756328.1\| orotate phosphoribosyltransferase [Escherichia coli CFT073], gi\|2611071... gi\|75514296 - gi\|75514296\|ref\|ZP_00736604.1\| COG0461: Orotate phosphoribosyltransferase [Escherichia coli 53638]	206.0	[0..1]	[213..6]
gi\|229356093, gi... - gi\|229506988\|ref\|ZP_04396496.1\| orotate phosphoribosyltransferase [Vibrio cholerae BX 330286], gi\|22... gi\|229512475, gi... - gi\|229512475\|ref\|ZP_04401947.1\| orotate phosphoribosyltransferase [Vibrio cholerae TMA 21], gi\|22935... gi\|229516305, gi... - gi\|229516305\|ref\|ZP_04405753.1\| orotate phosphoribosyltransferase [Vibrio cholerae RC9], gi\|22934673... gi\|229369151, gi... - gi\|229606496\|ref\|YP_002877144.1\| orotate phosphoribosyltransferase [Vibrio cholerae MJ-1236], gi\|229... gi\|124118745, gi... - gi\|153222605\|ref\|ZP_01953309.1\| orotate phosphoribosyltransferase [Vibrio cholerae MAK 757], gi\|1241... gi\|75830214, gi\|... - gi\|75830214\|ref\|ZP_00759496.1\| COG0461: Orotate phosphoribosyltransferase [Vibrio cholerae MO10], gi... gi\|126509508, gi... - gi\|153819944\|ref\|ZP_01972611.1\| orotate phosphoribosyltransferase [Vibrio cholerae NCTC 8457], gi\|12... gi\|229509358, gi... - gi\|229509358\|ref\|ZP_04398841.1\| orotate phosphoribosyltransferase [Vibrio cholerae B33], gi\|22935367... PYRE_VIBCH - (Q9KVD5) Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRT) (OPRTase) gi\|9654618, gi\|1... - gi\|9654618\|gb\|AAF93387.1\| orotate phosphoribosyltransferase [Vibrio cholerae O1 biovar El Tor str. N... gi\|150422455, gi... - gi\|254291598\|ref\|ZP_04962387.1\| orotate phosphoribosyltransferase [Vibrio cholerae AM-19226], gi\|197... gi\|227080432, gi... - gi\|227080432\|ref\|YP_002808983.1\| orotate phosphoribosyltransferase [Vibrio cholerae M66-2], gi\|22700...	206.0	[0..1]	[213..2]
gi\|30043343, gi\|... - gi\|30065082\|ref\|NP_839253.1\| orotate phosphoribosyltransferase [Shigella flexneri 2a str. 2457T], gi... PYRE_SHIFL - Orotate phosphoribosyltransferase OS=Shigella flexneri GN=pyrE PE=3 SV=4 gi\|56480392, gi\|... - gi\|56480392\|ref\|NP_709421.2\| orotate phosphoribosyltransferase [Shigella flexneri 2a str. 301], gi\|5...	206.0	[0..1]	[213..1]
PYRE_ECOL6 - Orotate phosphoribosyltransferase OS=Escherichia coli O6 GN=pyrE PE=3 SV=2 PYRE_ECOLI - Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRT) (OPRTase) - Escherichia coli PYRE_ECOLU - Orotate phosphoribosyltransferase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=pyrE PE... gi\|194435947, gi... - gi\|83588511\|ref\|ZP_00927135.1\| COG0461: Orotate phosphoribosyltransferase [Escherichia coli 101-1], ... PYRE_ECOHS - Orotate phosphoribosyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=pyrE PE=3 SV=1 gi\|75234800, gi\|... - gi\|75234800\|ref\|ZP_00719103.1\| COG0461: Orotate phosphoribosyltransferase [Escherichia coli E110019]... EG10808 - orotate phosphoribosyltransferase / Orotate phosphoribosyltransferase gi\|191170584, gi... - gi\|75242579\|ref\|ZP_00726323.1\| COG0461: Orotate phosphoribosyltransferase [Escherichia coli F11], gi... gi\|89110369, gi\|... - gi\|89110369\|ref\|AP_004149.1\| orotate phosphoribosyltransferase [Escherichia coli str. K-12 substr. W... PYRE_ECODH - Orotate phosphoribosyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=pyrE PE=3 SV=1 PYRE_ECOL6 - Orotate phosphoribosyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=... PYRE_ECO27 - Orotate phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=pyrE PE=3 ... gi\|188493202, gi... - gi\|188493202\|ref\|ZP_03000472.1\| orotate phosphoribosyltransferase [Escherichia coli 53638], gi\|18848... PYRE_ECO8A - Orotate phosphoribosyltransferase OS=Escherichia coli O8 (strain IAI1) GN=pyrE PE=3 SV=1 sp\|B7UM49\|PYRE_ECO27 - Orotate phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=pyrE PE=3 ... PYRE_ESCF3 - Orotate phosphoribosyltransferase OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 056... PYRE_ECO55 - Orotate phosphoribosyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=pyrE PE=3 SV=1 PYRE_ECO81 - Orotate phosphoribosyltransferase OS=Escherichia coli O81 (strain ED1a) GN=pyrE PE=3 SV=1 PYRE_ECOBW - Orotate phosphoribosyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=pyrE PE=3 SV... gi\|251786893, gi... - gi\|251786893\|ref\|YP_003001197.1\| hypothetical protein B21_03451 [Escherichia coli BL21], gi\|24237916... gi\|253322561, gi... - gi\|254290320\|ref\|YP_003056068.1\| orotate phosphoribosyltransferase [Escherichia coli BL21(DE3)], gi\|... gi\|253975471, gi... - gi\|254163570\|ref\|YP_003046678.1\| orotate phosphoribosyltransferase [Escherichia coli B str. REL606],... PYRE_ECOL5 - Orotate phosphoribosyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=pyrE PE=3 SV... PYRE_ECOLC - Orotate phosphoribosyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=pyrE... EG10808 - orotate phosphoribosyltransferase / Orotate phosphoribosyltransferase gi\|124500122, gi... - gi\|124528983\|ref\|ZP_01700129.1\| orotate phosphoribosyltransferase [Escherichia coli B], gi\|124500122...	206.0	[0..1]	[213..1]
gi\|89093848, gi\|... - gi\|89093848\|ref\|ZP_01166794.1\| orotate phosphoribosyltransferase [Oceanospirillum sp. MED92], gi\|890...	205.0	[0..1]	[213..1]
PYRE_SHIF8 - Orotate phosphoribosyltransferase OS=Shigella flexneri serotype 5b (strain 8401) GN=pyrE PE=3 SV=1	205.0	[0..1]	[213..1]
gi\|117625914, gi... - gi\|117625914\|ref\|YP_859237.1\| orotate phosphoribosyltransferase [Escherichia coli APEC O1], gi\|11551... gi\|91213159, gi\|... - gi\|91213159\|ref\|YP_543145.1\| orotate phosphoribosyltransferase [Escherichia coli UTI89], gi\|91074733... gi\|226902677, gi... - gi\|237703413\|ref\|ZP_04533894.1\| orotate phosphoribosyltransferase [Escherichia sp. 3_2_53FAA], gi\|22...	205.0	[0..1]	[213..6]
gi\|75208687 - gi\|75208687\|ref\|ZP_00708984.1\| COG0461: Orotate phosphoribosyltransferase [Escherichia coli B171] gi\|75179725 - gi\|75179725\|ref\|ZP_00699712.1\| COG0461: Orotate phosphoribosyltransferase [Shigella boydii BS512]	205.0	[0..1]	[213..6]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPYQRQFIE FALNKQVLKF GEFTLKSGRK SPYFFNAGLF NTGRDLALLG RFYAEALVDS  60
   61 GIEFDLLFGP AYKGIPIATT TAVALAEHHD KDLPYCFNRK EAKDHGEGGS LVGSALQGRV 120
  121 MLVDDVITAG TAIRESMEII QAHGATLAGV LISLDRQERG RGEISAIQEV ERDYGCKVIS 180
  181 IITLKDLIAY LEEKPDMAEH LAAVRAYREE FGV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.30103
Match:	1oroA
Description:	Orotate PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	3.1748712918814	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	3.0470646511978	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.97347277288245	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.21367942706564	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	2.02298774328915	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
purine binding	1.24786927434743	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.932396739123353	bayes_pls_golite062009
binding	0.847513071499147	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: