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View Structure Prediction Details

Protein: gi|190405970
Organism: Saccharomyces cerevisiae RM11-1a
Length: 575 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190405970.

Description E-value Query
Range
Subject
Range
gi|151944140 - gi|151944140|gb|EDN62433.1| U3 snoRNP protein [Saccharomyces cerevisiae YJM789]
UTP9_YEAST - U3 small nucleolar RNA-associated protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
UTP9 - Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is ...
gi|190405970 - gi|190405970|gb|EDV09237.1| U3 small nucleolar RNA-associated protein 9 [Saccharomyces cerevisiae RM...
gi|207344498 - gi|207344498|gb|EDZ71622.1| YHR196Wp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..575] [1..575]

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Predicted Domain #1
Region A:
Residues: [1-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSLDLVAS FSHDSTRFAF QASVAQKNNV DIYPLNETKD YVVNSSLVSH IDYETNDMKV  60
   61 SDVIFFGWCS DLIDTQSSNI KRKLDEDEGT GESSEQRCEN FFVNGFPDGR IVVYSSNGKD 120
  121 IVNIIKNKKE ILGADTDESD IWILDSDKVV KKLQYNNSKP LKTFTLVDGK DDEIVHFQIL 180
  181 HQNGTLLVCI ITKQMVYIVD PSKRRPSTKY SFEISDAVAC EFSSDGKYLL IANNEELIAY 240
  241 DLKEDSKLIQ SWPVQVKTLK TLDDLIMALT TDGKINNYKI GEADKVCSIV VNEDLEIIDF 300
  301 TPINSKQQVL ISWLNVNEPN FESISLKEIE TQGYITINKN EKNNADEADQ KKLEEKEEEA 360
  361 QPEVQHEKK

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 1.54
Match: 1tbgA
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3.17730118508639 bayes_pls_golite062009
snoRNA binding 3.12844073350845 bayes_pls_golite062009
RNA binding 2.97000647761702 bayes_pls_golite062009
binding 2.38386546684697 bayes_pls_golite062009
transcription regulator activity 2.36560618519891 bayes_pls_golite062009
nucleic acid binding 2.30172153305516 bayes_pls_golite062009
protein binding 2.19549049361621 bayes_pls_golite062009
DNA binding 1.74970945772818 bayes_pls_golite062009
structural molecule activity 1.32884088690898 bayes_pls_golite062009
transcription activator activity 1.24665557926829 bayes_pls_golite062009
transcription factor activity 1.10790917305704 bayes_pls_golite062009
transcription repressor activity 0.561205988591905 bayes_pls_golite062009
cytoskeletal protein binding 0.435475723571992 bayes_pls_golite062009
transcription factor binding 0.421428497325728 bayes_pls_golite062009
ligase activity 0.279385134085056 bayes_pls_golite062009
transcription cofactor activity 0.203779337313278 bayes_pls_golite062009
mRNA binding 0.0554986997005726 bayes_pls_golite062009
transcription corepressor activity 0.00328955300255629 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [370-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETETKINKKV SKSDQVEIAN ILSSHLEANS TEILDDLMSG SWTEPEIKKF ILTKINTVDH  60
   61 LSKIFLTISK SITQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 1.64
Match: 1erjC
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [444-575]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPWNEENLLP LWLKWLLTLK SGELNSIKDK HTKKNCKHLK SALRSSEEIL PVLLGIQGRL  60
   61 EMLRRQAKLR EDLAQLSMQE GEDDEIEVIE HSNVISNPLQ DQASPVEKLE PDSIVYANGE 120
  121 SDEFVDASEY KD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle