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View Structure Prediction Details

Protein: gi|221313116
Organism: Bacillus subtilis subsp. subtilis str. NCIB 3610
Length: 331 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|221313116.

Description E-value Query
Range
Subject
Range
gi|50119681, gi|... - gi|50119681|ref|YP_048848.1| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...
347.0 [0..1] [324..1]

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Predicted Domain #1
Region A:
Residues: [1-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYTSIADTG IEASRIGLGT WAIGGTMWGG TDEKTSIETI RAALDQGITL IDTAPAYGFG  60
   61 QSEEIVGKAI KEYGKRDQVI LATKTALDWK NNQLFRHANR ARIVEEVENS LKRLQTDYID 120
  121 LYQVHWPDPL VPIEETAEVM KELYDAGKIR AIGVSNFSIE QMDTFRAVAP LHTIQPPYNL 180
  181 FEREMEESVL PYAKDNKITT LLYGSLCRGL LTGKMTEEYT FEGDDLRNHD PKFQKPRFKE 240
  241 YLSAVNQLDK LAKTRYGKSV IHLAVRWILD QPGADIALWG ARKPGQLEAL SEITGWTLNS 300
  301 EDQKDINTIL ENTISDPVGP EFMAPPTREE I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.69897
Match: 1pz1A
Description: Structure of NADPH-dependent family 11 aldo-keto reductase AKR11B(holo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 7.51963276589303 bayes_pls_golite062009
voltage-gated potassium channel activity 7.40239094355354 bayes_pls_golite062009
voltage-gated cation channel activity 6.67507110634301 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.588881463055 bayes_pls_golite062009
voltage-gated ion channel activity 6.52286930358188 bayes_pls_golite062009
voltage-gated channel activity 6.50716590143831 bayes_pls_golite062009
cation channel activity 5.72172645555113 bayes_pls_golite062009
ion channel activity 5.15119282480682 bayes_pls_golite062009
passive transmembrane transporter activity 5.07214658557001 bayes_pls_golite062009
channel activity 5.07214658557001 bayes_pls_golite062009
substrate-specific channel activity 5.02503292701043 bayes_pls_golite062009
gated channel activity 4.92848832197692 bayes_pls_golite062009
aldo-keto reductase activity 3.79117514230146 bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity 3.25535446462297 bayes_pls_golite062009
ion transmembrane transporter activity 2.63772951680109 bayes_pls_golite062009
cation transmembrane transporter activity 2.58068601897668 bayes_pls_golite062009
aryl-alcohol dehydrogenase activity 2.5168190536972 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.46488926936937 bayes_pls_golite062009
aldehyde reductase activity 2.19831490122079 bayes_pls_golite062009
catalytic activity 1.68179794468736 bayes_pls_golite062009
transporter activity 1.24767072239634 bayes_pls_golite062009
binding 1.15657176144267 bayes_pls_golite062009
transmembrane transporter activity 1.03420335553507 bayes_pls_golite062009
potassium channel regulator activity 1.03017249802223 bayes_pls_golite062009
substrate-specific transporter activity 0.783004917746429 bayes_pls_golite062009
oxidoreductase activity 0.409822872480823 bayes_pls_golite062009
protein binding 0.220529867719707 bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity 0.207008954325429 bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 0.207008954325429 bayes_pls_golite062009
0.139676323362391 bayes_pls_golite062009
channel regulator activity 0.12154513851913 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0465377885825481 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.0143508436041874 bayes_pls_golite062009

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