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View Structure Prediction Details

Protein: MBD4L_ARATH
Organism: Arabidopsis thaliana
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MBD4L_ARATH.

Description E-value Query
Range
Subject
Range
gi|6648205 - gi|6648205|gb|AAF21203.1|AC013483_27 hypothetical protein [Arabidopsis thaliana]
444.0 [0..27] [445..1]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPPIIYKYK RRKDRRLGRD DDSSVMMTRR RPDSDFIEVS DENRSFALFK EDDEKNRDLG  60
   61 LVDDGSTNLV LQCHDDGCSL EKDNSNSLDD LFSGFVYKGV RRRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDDFGSITTS NLVSPQIADD DDDSVSDSHI ERQECSEFHV EVRRVSPYFQ GSTVSQQSKE  60
   61 GCDSDSVCSK EGCSKVQAKV PRVSPYFQAS TISQCDSDIV SSSQSGRNYR KGSSKRQVKV 120
  121 RRVSPYFQES TVSEQPNQAP KGLRNYFKVV KVSRYFHADG IQVNESQKEK SRNVRKTPIV 180
  181 SPVL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [289-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLSQKTDDVY LRKTPDNTWV PPRSPCNLLQ EDHWHDPWRV LVICMLLNKT SGAQTRGVIS  60
   61 DLFGLCTDAK TATEVKEEEI ENLIKPLGLQ KKRTKMIQRL SLEYLQESWT HVTQLHGVGK 120
  121 YAADAYAIFC NGNWDRVKPN DHMLNYYWDY LRIRYKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.154902
Match: 1ngnA
Description: Mismatch-specific thymine glycosylase domain of the methyl-GpG binding protein mbd4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.60340066066017 bayes_pls_golite062009
hydrolase activity 0.26415395380306 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 0.10668773971346 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 0.10147260280693 bayes_pls_golite062009
DNA N-glycosylase activity 0.10080290288194 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle