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View Structure Prediction Details

Protein: MBD4L_ARATH
Organism: Arabidopsis thaliana
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MBD4L_ARATH.

Description E-value Query
Range
Subject
Range
gi|6648205 - gi|6648205|gb|AAF21203.1|AC013483_27 hypothetical protein [Arabidopsis thaliana]
444.0 [0..27] [445..1]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPPIIYKYK RRKDRRLGRD DDSSVMMTRR RPDSDFIEVS DENRSFALFK EDDEKNRDLG  60
   61 LVDDGSTNLV LQCHDDGCSL EKDNSNSLDD LFSGFVYKGV RRRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDDFGSITTS NLVSPQIADD DDDSVSDSHI ERQECSEFHV EVRRVSPYFQ GSTVSQQSKE  60
   61 GCDSDSVCSK EGCSKVQAKV PRVSPYFQAS TISQCDSDIV SSSQSGRNYR KGSSKRQVKV 120
  121 RRVSPYFQES TVSEQPNQAP KGLRNYFKVV KVSRYFHADG IQVNESQKEK SRNVRKTPIV 180
  181 SPVL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [289-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLSQKTDDVY LRKTPDNTWV PPRSPCNLLQ EDHWHDPWRV LVICMLLNKT SGAQTRGVIS  60
   61 DLFGLCTDAK TATEVKEEEI ENLIKPLGLQ KKRTKMIQRL SLEYLQESWT HVTQLHGVGK 120
  121 YAADAYAIFC NGNWDRVKPN DHMLNYYWDY LRIRYKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.154902
Match: 1ngnA
Description: Mismatch-specific thymine glycosylase domain of the methyl-GpG binding protein mbd4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.60340066066017 bayes_pls_golite062009
hydrolase activity 0.26415395380306 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 0.10668773971346 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 0.10147260280693 bayes_pls_golite062009
DNA N-glycosylase activity 0.10080290288194 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle