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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.754649006131]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein serine/threonine phosphatase complex 6.8716E-6 2 17 2 6292
calcineurin complex 1.2712E-3 2 4 1 6292
protein phosphatase type 2A complex 1.9064E-3 2 6 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

signaling 1.598E-3 2 252 2 6292
reproduction 2.7096E-3 2 328 2 6292
adaptation of signaling pathway 4.4455E-3 2 14 1 6292
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion 4.4455E-3 2 14 1 6292
mitotic cell cycle spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of nuclear division 6.6645E-3 2 21 1 6292
negative regulation of mitosis 6.6645E-3 2 21 1 6292
negative regulation of mitotic metaphase/anaphase transition 6.6645E-3 2 21 1 6292
spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of cell cycle 6.9813E-3 2 22 1 6292
spindle checkpoint 7.9314E-3 2 25 1 6292
regulation of mitotic metaphase/anaphase transition 7.9314E-3 2 25 1 6292
mitotic cell cycle spindle checkpoint 7.9314E-3 2 25 1 6292
mitotic cell cycle checkpoint 8.8811E-3 2 28 1 6292
regulation of signaling pathway 8.8811E-3 2 28 1 6292
protein amino acid dephosphorylation 8.8811E-3 2 28 1 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
regulation of nuclear division 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292
regulation of mitosis 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein serine/threonine phosphatase activity 1.6421E-5 2 26 2 6292
phosphoprotein phosphatase activity 4.5626E-5 2 43 2 6292
metal ion binding 7.5032E-5 2 55 2 6292
ion binding 7.7811E-5 2 56 2 6292
cation binding 7.7811E-5 2 56 2 6292
phosphatase activity 1.8902E-4 2 87 2 6292
phosphoric ester hydrolase activity 2.6026E-4 2 102 2 6292
calcium-dependent protein serine/threonine phosphatase activity 9.5344E-4 2 3 1 6292
calcium ion binding 2.224E-3 2 7 1 6292
hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle