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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.037] [SVM Score: 0.838250652709]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

positive regulation of DNA replication 5.0527E-8 2 2 2 6292
regulation of S phase 1.5158E-7 2 3 2 6292
regulation of S phase of mitotic cell cycle 1.5158E-7 2 3 2 6292
positive regulation of DNA metabolic process 1.5158E-7 2 3 2 6292
premeiotic DNA synthesis 5.0527E-7 2 5 2 6292
S phase 2.2737E-6 2 10 2 6292
S phase of mitotic cell cycle 2.2737E-6 2 10 2 6292
regulation of cyclin-dependent protein kinase activity 4.5979E-6 2 14 2 6292
regulation of DNA replication 5.3053E-6 2 15 2 6292
regulation of kinase activity 1.6421E-5 2 26 2 6292
regulation of protein kinase activity 1.6421E-5 2 26 2 6292
regulation of transferase activity 1.6421E-5 2 26 2 6292
regulation of DNA metabolic process 2.3495E-5 2 31 2 6292
regulation of phosphorylation 2.3495E-5 2 31 2 6292
regulation of phosphorus metabolic process 3.552E-5 2 38 2 6292
regulation of phosphate metabolic process 3.552E-5 2 38 2 6292
regulation of catalytic activity 4.7798E-5 2 44 2 6292
regulation of molecular function 4.7798E-5 2 44 2 6292
G1/S transition of mitotic cell cycle 6.1895E-5 2 50 2 6292
regulation of mitotic cell cycle 1.2556E-4 2 71 2 6292
regulation of cell cycle process 1.6371E-4 2 81 2 6292
interphase of mitotic cell cycle 2.3525E-4 2 97 2 6292
interphase 2.3525E-4 2 97 2 6292
spindle assembly 3.1786E-4 2 1 1 6292
positive regulation of nitrogen compound metabolic process 3.4879E-4 2 118 2 6292
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.4879E-4 2 118 2 6292
positive regulation of macromolecule biosynthetic process 3.4879E-4 2 118 2 6292
positive regulation of biosynthetic process 3.6682E-4 2 121 2 6292
positive regulation of cellular biosynthetic process 3.6682E-4 2 121 2 6292
DNA replication 3.791E-4 2 123 2 6292
positive regulation of macromolecule metabolic process 3.979E-4 2 126 2 6292
positive regulation of metabolic process 4.1715E-4 2 129 2 6292
positive regulation of cellular metabolic process 4.1715E-4 2 129 2 6292
regulation of cell cycle 4.3024E-4 2 131 2 6292
positive regulation of cellular process 4.6384E-4 2 136 2 6292
positive regulation of biological process 4.7071E-4 2 137 2 6292
phosphorylation 8.0494E-4 2 179 2 6292
phosphorus metabolic process 1.3191E-3 2 229 2 6292
phosphate metabolic process 1.3191E-3 2 229 2 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
cell cycle phase 3.5621E-3 2 376 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
cell cycle process 6.0534E-3 2 490 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
cell cycle 6.95E-3 2 525 2 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292
G2/M transition of mitotic cell cycle 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cyclin-dependent protein kinase regulator activity 1.6421E-5 2 26 2 6292
protein kinase regulator activity 5.2295E-5 2 46 2 6292
kinase regulator activity 5.9419E-5 2 49 2 6292
enzyme regulator activity 1.0773E-3 2 207 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle