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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.878929107389]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

CBF3 complex 3.0316E-7 2 4 2 6292
condensed nuclear chromosome kinetochore 5.9419E-5 2 49 2 6292
condensed chromosome kinetochore 5.9419E-5 2 49 2 6292
condensed chromosome, centromeric region 7.5032E-5 2 55 2 6292
condensed nuclear chromosome, centromeric region 7.5032E-5 2 55 2 6292
kinetochore 8.9432E-5 2 60 2 6292
chromosome, centromeric region 1.1171E-4 2 67 2 6292
condensed nuclear chromosome 1.8468E-4 2 86 2 6292
condensed chromosome 2.2085E-4 2 94 2 6292
nuclear chromosome part 9.0721E-4 2 190 2 6292
nuclear chromosome 1.3075E-3 2 228 2 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
spindle midzone 2.224E-3 2 7 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitotic cell cycle 1.6363E-3 2 255 2 6292
M phase 2.1762E-3 2 294 2 6292
cell cycle phase 3.5621E-3 2 376 2 6292
cell cycle process 6.0534E-3 2 490 2 6292
mitotic cell cycle spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of mitotic metaphase/anaphase transition 6.6645E-3 2 21 1 6292
mitotic spindle elongation 6.6645E-3 2 21 1 6292
spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of nuclear division 6.6645E-3 2 21 1 6292
negative regulation of mitosis 6.6645E-3 2 21 1 6292
spindle elongation 6.6645E-3 2 21 1 6292
cell cycle 6.95E-3 2 525 2 6292
negative regulation of cell cycle 6.9813E-3 2 22 1 6292
regulation of mitotic metaphase/anaphase transition 7.9314E-3 2 25 1 6292
mitotic cell cycle spindle checkpoint 7.9314E-3 2 25 1 6292
spindle checkpoint 7.9314E-3 2 25 1 6292
mitotic cell cycle checkpoint 8.8811E-3 2 28 1 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
regulation of nuclear division 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292
regulation of mitosis 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

centromeric DNA binding 1.4147E-6 2 8 2 6292
DNA bending activity 3.9411E-6 2 13 2 6292
sequence-specific DNA binding 6.1895E-5 2 50 2 6292
DNA binding 1.6492E-3 2 256 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle