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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.92675623923]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomerase holoenzyme complex 3.0316E-7 2 4 2 6292
telomerase catalytic core complex 3.1786E-4 2 1 1 6292
nucleolus 1.1194E-3 2 211 2 6292
nuclear lumen 5.1728E-3 2 453 2 6292
ribonucleoprotein complex 6.6615E-3 2 514 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomere maintenance via telomere lengthening 3.9411E-6 2 13 2 6292
telomere maintenance via telomerase 3.9411E-6 2 13 2 6292
RNA-dependent DNA replication 3.9411E-6 2 13 2 6292
DNA replication 3.791E-4 2 123 2 6292
anatomical structure homeostasis 2.0592E-3 2 286 2 6292
telomere organization 2.0592E-3 2 286 2 6292
telomere maintenance 2.0592E-3 2 286 2 6292
homeostatic process 4.1951E-3 2 408 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
chromosome organization 7.7677E-3 2 555 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomerase activity 3.0316E-7 2 4 2 6292
RNA-directed DNA polymerase activity 2.4511E-4 2 99 2 6292
telomeric template RNA reverse transcriptase activity 3.1786E-4 2 1 1 6292
DNA polymerase activity 3.312E-4 2 115 2 6292
nucleotidyltransferase activity 7.0879E-4 2 168 2 6292
transferase activity, transferring phosphorus-containing groups 4.4459E-3 2 420 2 6292
single-stranded DNA binding 5.0798E-3 2 16 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle