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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.955434902476]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
PEP3
  • fungal-type vacuole membrane
  • extrinsic to vacuolar membrane
  • HOPS complex
    		•
  • response to drug
  • vesicle docking during exocytosis
  • late endosome to vacuole transport
  • telomere maintenance
  • vacuole fusion, non-autophagic
  • Golgi to endosome transport
    		•
  • protein binding
    		•
    VPS33
  • fungal-type vacuole membrane
  • cytosol
  • HOPS complex
    		•
  • late endosome to vacuole transport
  • vacuole fusion, non-autophagic
  • Golgi to endosome transport
    		•
  • ATP binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    HOPS complex 7.579E-7 2 6 2 6292
    fungal-type vacuole membrane 1.3647E-4 2 74 2 6292
    vacuolar membrane 3.1973E-4 2 113 2 6292
    vacuolar part 3.6682E-4 2 121 2 6292
    fungal-type vacuole 6.2668E-4 2 158 2 6292
    lytic vacuole 6.2668E-4 2 158 2 6292
    storage vacuole 6.2668E-4 2 158 2 6292
    extrinsic to vacuolar membrane 6.3568E-4 2 2 1 6292
    vacuole 1.0983E-3 2 209 2 6292
    extrinsic to organelle membrane 3.811E-3 2 12 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Golgi to endosome transport 2.779E-6 2 11 2 6292
    late endosome to vacuole transport 1.3945E-5 2 24 2 6292
    vacuole fusion, non-autophagic 1.7735E-5 2 27 2 6292
    vacuole organization 5.2295E-5 2 46 2 6292
    endosome transport 6.6999E-5 2 52 2 6292
    membrane fusion 1.1171E-4 2 67 2 6292
    cellular membrane fusion 1.1171E-4 2 67 2 6292
    post-Golgi vesicle-mediated transport 1.151E-4 2 68 2 6292
    vacuolar transport 3.312E-4 2 115 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    membrane organization 9.8542E-4 2 198 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    vesicle docking during exocytosis 3.811E-3 2 12 1 6292
    membrane docking 4.4455E-3 2 14 1 6292
    vesicle docking 4.4455E-3 2 14 1 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ATP binding 7.6148E-3 2 24 1 6292
    adenyl ribonucleotide binding 7.9314E-3 2 25 1 6292
    adenyl nucleotide binding 9.5139E-3 2 30 1 6292
    purine nucleoside binding 9.8303E-3 2 31 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle