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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.37005733601]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin cortical patch 4.1432E-5 2 41 2 6292
cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
cortical cytoskeleton 6.6999E-5 2 52 2 6292
actin cytoskeleton 1.8038E-4 2 85 2 6292
cell cortex part 2.304E-4 2 96 2 6292
cell cortex 2.974E-4 2 109 2 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

bipolar cellular bud site selection 2.8346E-5 2 34 2 6292
actin filament organization 1.151E-4 2 68 2 6292
cytokinesis, site selection 1.3647E-4 2 74 2 6292
cellular bud site selection 1.3647E-4 2 74 2 6292
cell cycle cytokinesis 1.5966E-4 2 80 2 6292
establishment of cell polarity 1.7614E-4 2 84 2 6292
establishment or maintenance of cell polarity 1.8038E-4 2 85 2 6292
asexual reproduction 2.0236E-4 2 90 2 6292
cell budding 2.0236E-4 2 90 2 6292
cytokinetic process 2.1151E-4 2 92 2 6292
cytokinesis 3.1407E-4 2 112 2 6292
sequestering of actin monomers 3.1786E-4 2 1 1 6292
actin cytoskeleton organization 3.1973E-4 2 113 2 6292
actin filament-based process 3.4287E-4 2 117 2 6292
cell morphogenesis 3.9158E-4 2 125 2 6292
cellular component morphogenesis 4.7763E-4 2 138 2 6292
cell division 5.275E-4 2 145 2 6292
regulation of actin polymerization or depolymerization 9.5344E-4 2 3 1 6292
protein polymerization 9.5344E-4 2 3 1 6292
regulation of actin cytoskeleton organization 9.5344E-4 2 3 1 6292
regulation of protein polymerization 9.5344E-4 2 3 1 6292
negative regulation of protein polymerization 9.5344E-4 2 3 1 6292
negative regulation of protein complex assembly 9.5344E-4 2 3 1 6292
actin filament polymerization 9.5344E-4 2 3 1 6292
regulation of actin filament polymerization 9.5344E-4 2 3 1 6292
regulation of actin filament length 9.5344E-4 2 3 1 6292
negative regulation of actin filament polymerization 9.5344E-4 2 3 1 6292
regulation of actin filament-based process 9.5344E-4 2 3 1 6292
reproduction of a single-celled organism 1.1841E-3 2 217 2 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
anatomical structure morphogenesis 1.6621E-3 2 257 2 6292
anatomical structure development 1.7012E-3 2 260 2 6292
cellular developmental process 1.9175E-3 2 276 2 6292
negative regulation of cytoskeleton organization 2.5415E-3 2 8 1 6292
reproduction 2.7096E-3 2 328 2 6292
developmental process 2.7595E-3 2 331 2 6292
actin polymerization or depolymerization 2.859E-3 2 9 1 6292
regulation of protein complex assembly 3.4937E-3 2 11 1 6292
regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
cell cycle process 6.0534E-3 2 490 2 6292
regulation of cytoskeleton organization 6.3477E-3 2 20 1 6292
cell cycle 6.95E-3 2 525 2 6292
maintenance of protein location 8.248E-3 2 26 1 6292
maintenance of location 8.8811E-3 2 28 1 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin binding 1.0611E-5 2 21 2 6292
cytoskeletal protein binding 8.6451E-5 2 59 2 6292
actin monomer binding 6.3568E-4 2 2 1 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle