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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.810209332798]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SEC62
  • endoplasmic reticulum membrane
  • Sec62/Sec63 complex
    		•
  • posttranslational protein targeting to membrane
    		•
  • protein binding
  • protein transporter activity
    		•
    SEC66
  • endoplasmic reticulum membrane
  • Sec62/Sec63 complex
    		•
  • filamentous growth
  • posttranslational protein targeting to membrane
    		•
  • protein transporter activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Sec62/Sec63 complex 5.0527E-7 2 5 2 6292
    endoplasmic reticulum Sec complex 5.0527E-7 2 5 2 6292
    rough endoplasmic reticulum 3.3348E-6 2 12 2 6292
    rough endoplasmic reticulum membrane 3.3348E-6 2 12 2 6292
    endoplasmic reticulum membrane 4.4352E-4 2 133 2 6292
    endoplasmic reticulum part 5.6464E-4 2 150 2 6292
    subsynaptic reticulum 5.6464E-4 2 150 2 6292
    nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
    endoplasmic reticulum 3.3381E-3 2 364 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    posttranslational protein targeting to membrane 1.819E-6 2 9 2 6292
    protein targeting to ER 2.6678E-5 2 33 2 6292
    protein localization in endoplasmic reticulum 3.9411E-5 2 40 2 6292
    protein targeting to membrane 6.6999E-5 2 52 2 6292
    protein localization in organelle 5.5711E-4 2 149 2 6292
    protein targeting 1.3892E-3 2 235 2 6292
    intracellular protein transport 1.6363E-3 2 255 2 6292
    protein transport 1.8213E-3 2 269 2 6292
    establishment of protein localization 1.8485E-3 2 271 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein transporter activity 8.3521E-5 2 58 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle