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The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The volume enclosed by the membranes of the rough endoplasmic reticulum. An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). The lipid bilayer surrounding the rough endoplasmic reticulum. Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: rough endoplasmic reticulum
Acc: GO:0005791
Aspect: Cellular Component
Desc: The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
Synonyms:
  • RER
  • rough ER
Proteins in PDR annotated with:
   This term: 53 [Search]
   Term or descendants: 124 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005791 - rough endoplasmic reticulum (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle