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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rfc3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 2.2161E-7 8 11 3 6292
replication fork 1.5136E-5 8 42 3 6292
proteasome accessory complex 3.5318E-4 8 23 2 6292
proteasome regulatory particle 3.5318E-4 8 23 2 6292
proteasome complex 1.5498E-3 8 48 2 6292
chromosomal part 2.5676E-3 8 237 3 6292
chromosome 3.8858E-3 8 274 3 6292
macromolecular complex 5.1894E-3 8 1635 6 6292
protein complex 6.5954E-3 8 1137 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 6.0965E-7 8 15 3 6292
mismatch repair 3.8912E-6 8 27 3 6292
DNA strand elongation 5.9655E-6 8 31 3 6292
DNA strand elongation involved in DNA replication 5.9655E-6 8 31 3 6292
sister chromatid cohesion 6.5787E-6 8 32 3 6292
DNA-dependent DNA replication 1.1399E-4 8 82 3 6292
DNA replication 3.8004E-4 8 123 3 6292
chromosome segregation 4.2742E-4 8 128 3 6292
DNA repair 1.3988E-3 8 192 3 6292
response to DNA damage stimulus 2.5366E-3 8 236 3 6292
cellular response to stress 4.565E-3 8 290 3 6292
cellular response to stimulus 9.6717E-3 8 379 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA clamp loader activity 4.7121E-8 8 7 3 6292
protein-DNA loading ATPase activity 4.7121E-8 8 7 3 6292
DNA-dependent ATPase activity 3.4321E-5 8 55 3 6292
ATPase activity 7.7406E-5 8 211 4 6292
nucleoside-triphosphatase activity 4.3453E-4 8 329 4 6292
hydrolase activity, acting on acid anhydrides 5.6934E-4 8 353 4 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.6934E-4 8 353 4 6292
pyrophosphatase activity 5.6934E-4 8 353 4 6292
ATPase activity, coupled 6.6794E-4 8 149 3 6292
endopeptidase activity 1.9586E-3 8 54 2 6292
hydrolase activity 2.4085E-3 8 911 5 6292
catalytic activity 3.0336E-3 8 2150 7 6292
DNA binding 3.2017E-3 8 256 3 6292
peptidase activity, acting on L-amino acid peptides 5.9534E-3 8 95 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle