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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rfa3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AAC3
  • mitochondrion
  • mitochondrial inner membrane
  • anaerobic respiration
  • ATP:ADP antiporter activity
  • ARO1
  • cytoplasm
  • aromatic amino acid family biosynthetic process
  • shikimate kinase activity
  • 3-dehydroquinate dehydratase activity
  • 3-phosphoshikimate 1-carboxyvinyltransferase activity
  • 3-dehydroquinate synthase activity
  • shikimate 5-dehydrogenase activity
  • CYS4
  • cytoplasm
  • mitochondrion
  • response to drug
  • cysteine biosynthetic process
  • cystathionine beta-synthase activity
  • HEF3
  • cytosolic ribosome
  • translational elongation
  • ATPase activity
  • translation elongation factor activity
  • HOR2
  • nucleus
  • cytoplasm
  • carbohydrate metabolic process
  • response to osmotic stress
  • glycerol biosynthetic process
  • glycerol-1-phosphatase activity
  • HXT7
  • mitochondrion
  • plasma membrane
  • hexose transport
  • fructose transmembrane transporter activity
  • glucose transmembrane transporter activity
  • mannose transmembrane transporter activity
  • MTC5
  • fungal-type vacuole membrane
  • biological_process
  • molecular_function
  • PGM2
  • cytosol
  • response to temperature stimulus
  • energy reserve metabolic process
  • UDP-glucose metabolic process
  • trehalose biosynthetic process
  • alcohol metabolic process
  • glucose metabolic process
  • cellular calcium ion homeostasis
  • vacuolar protein catabolic process
  • carbohydrate metabolic process
  • glycogen biosynthetic process
  • glucose 6-phosphate metabolic process
  • cellular carbohydrate metabolic process
  • galactose catabolic process
  • glucose 1-phosphate metabolic process
  • cellular cation homeostasis
  • phosphoglucomutase activity
  • RFA3
  • chromosome, telomeric region
  • DNA replication factor A complex
  • DNA strand elongation involved in DNA replication
  • double-strand break repair via homologous recombination
  • DNA recombination
  • nucleotide-excision repair
  • DNA unwinding involved in replication
  • postreplication repair
  • DNA replication, synthesis of RNA primer
  • DNA binding
  • RHR2
  • nucleus
  • cytoplasm
  • response to drug
  • response to osmotic stress
  • glycerol biosynthetic process
  • glycerol-1-phosphatase activity
  • YJR141W
  • cellular_component
  • mRNA processing
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA replication factor A complex 5.2364E-3 11 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    alditol biosynthetic process 1.6642E-5 11 4 2 6292
    glycerol biosynthetic process 1.6642E-5 11 4 2 6292
    polyol biosynthetic process 1.6642E-5 11 4 2 6292
    energy derivation by oxidation of organic compounds 8.7579E-5 11 149 4 6292
    alditol metabolic process 1.241E-4 11 10 2 6292
    glycerol metabolic process 1.241E-4 11 10 2 6292
    generation of precursor metabolites and energy 2.4882E-4 11 195 4 6292
    cellular carbohydrate biosynthetic process 2.8155E-4 11 78 3 6292
    polyol metabolic process 4.1874E-4 11 18 2 6292
    carbohydrate biosynthetic process 4.4404E-4 11 91 3 6292
    fermentation 5.1901E-4 11 20 2 6292
    response to abiotic stimulus 9.2735E-4 11 117 3 6292
    small molecule biosynthetic process 1.4476E-3 11 310 4 6292
    alcohol biosynthetic process 2.8778E-3 11 47 2 6292
    cysteine biosynthetic process 3.4937E-3 11 2 1 6292
    glucose 6-phosphate metabolic process 3.4937E-3 11 2 1 6292
    anaerobic respiration 3.4937E-3 11 2 1 6292
    glucose 1-phosphate metabolic process 3.4937E-3 11 2 1 6292
    UDP-glucose metabolic process 5.2364E-3 11 3 1 6292
    alcohol metabolic process 5.6506E-3 11 220 3 6292
    small molecule metabolic process 6.2697E-3 11 760 5 6292
    response to stimulus 6.4879E-3 11 766 5 6292
    cysteine metabolic process 6.9763E-3 11 4 1 6292
    cellular biosynthetic process 7.3437E-3 11 1567 7 6292
    response to osmotic stress 7.5696E-3 11 77 2 6292
    biosynthetic process 8.3665E-3 11 1602 7 6292
    DNA replication, synthesis of RNA primer 8.7135E-3 11 5 1 6292
    galactose catabolic process 8.7135E-3 11 5 1 6292
    cellular carbohydrate metabolic process 9.1838E-3 11 262 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    glycerol-1-phosphatase activity 8.329E-6 11 3 2 6292
    hydro-lyase activity 9.5242E-4 11 27 2 6292
    carbon-oxygen lyase activity 1.6949E-3 11 36 2 6292
    3-dehydroquinate dehydratase activity 1.7483E-3 11 1 1 6292
    3-dehydroquinate synthase activity 1.7483E-3 11 1 1 6292
    cystathionine beta-synthase activity 1.7483E-3 11 1 1 6292
    shikimate 5-dehydrogenase activity 1.7483E-3 11 1 1 6292
    3-phosphoshikimate 1-carboxyvinyltransferase activity 1.7483E-3 11 1 1 6292
    shikimate kinase activity 1.7483E-3 11 1 1 6292
    phosphoglucomutase activity 3.4937E-3 11 2 1 6292
    ATP:ADP antiporter activity 5.2364E-3 11 3 1 6292
    carbon-oxygen lyase activity, acting on phosphates 5.2364E-3 11 3 1 6292
    phosphatase activity 9.5862E-3 11 87 2 6292
    lyase activity 9.7997E-3 11 88 2 6292

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