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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cof1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin cortical patch 2.0999E-5 9 41 3 6292
cortical actin cytoskeleton 4.3192E-5 9 52 3 6292
cortical cytoskeleton 4.3192E-5 9 52 3 6292
actin cytoskeleton 1.8851E-4 9 85 3 6292
cell cortex part 2.7054E-4 9 96 3 6292
cell cortex 3.9379E-4 9 109 3 6292
cytoskeletal part 2.3397E-3 9 201 3 6292
cytoskeleton 2.8751E-3 9 216 3 6292
cytoplasm 5.7975E-3 9 3552 9 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin filament depolymerization 1.0898E-5 9 4 2 6292
actin polymerization or depolymerization 6.5143E-5 9 9 2 6292
protein depolymerization 8.1369E-5 9 10 2 6292
cellular protein complex disassembly 1.3113E-3 9 39 2 6292
protein complex disassembly 1.3113E-3 9 39 2 6292
cellular macromolecular complex disassembly 1.3793E-3 9 40 2 6292
macromolecular complex disassembly 1.3793E-3 9 40 2 6292
actin filament severing 1.4304E-3 9 1 1 6292
Ras protein signal transduction 1.449E-3 9 41 2 6292
cellular component disassembly 1.6679E-3 9 44 2 6292
cytoskeleton organization 3.4816E-3 9 231 3 6292
small GTPase mediated signal transduction 3.502E-3 9 64 2 6292
actin filament organization 3.9454E-3 9 68 2 6292
G-protein signaling, coupled to cyclic nucleotide second messenger 4.2857E-3 9 3 1 6292
G-protein signaling, coupled to cAMP nucleotide second messenger 4.2857E-3 9 3 1 6292
age-dependent response to oxidative stress 9.9746E-3 9 7 1 6292
cyclic-nucleotide-mediated signaling 9.9746E-3 9 7 1 6292
age-dependent response to oxidative stress involved in chronological cell aging 9.9746E-3 9 7 1 6292
age-dependent general metabolic decline involved in chronological cell aging 9.9746E-3 9 7 1 6292
cAMP-mediated signaling 9.9746E-3 9 7 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

phosphorus-oxygen lyase activity 1.4304E-3 9 1 1 6292
adenylate cyclase binding 1.4304E-3 9 1 1 6292
adenylate cyclase activity 1.4304E-3 9 1 1 6292
cyclase activity 2.859E-3 9 2 1 6292
cyclin-dependent protein kinase inhibitor activity 4.2857E-3 9 3 1 6292
protein serine/threonine kinase inhibitor activity 5.7106E-3 9 4 1 6292
protein binding 7.4954E-3 9 612 4 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle