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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdh1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chaperonin-containing T-complex 4.981E-5 6 12 2 6292
cytosolic part 5.3155E-3 6 122 2 6292
macromolecular complex 5.5477E-3 6 1635 5 6292
non-membrane-bounded organelle 6.2191E-3 6 959 4 6292
intracellular non-membrane-bounded organelle 6.2191E-3 6 959 4 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cellular protein metabolic process 7.4048E-4 6 1074 5 6292
cytoskeleton organization 8.999E-4 6 231 3 6292
protein metabolic process 9.7146E-4 6 1136 5 6292
mitotic cell cycle 1.2014E-3 6 255 3 6292
M phase 1.8178E-3 6 294 3 6292
activation of mitotic anaphase-promoting complex activity 1.9064E-3 6 2 1 6292
activation of anaphase-promoting complex activity 1.9064E-3 6 2 1 6292
positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.9064E-3 6 2 1 6292
positive regulation of nuclear division 1.9064E-3 6 2 1 6292
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.9064E-3 6 2 1 6292
positive regulation of mitotic metaphase/anaphase transition 1.9064E-3 6 2 1 6292
positive regulation of mitosis 1.9064E-3 6 2 1 6292
positive regulation of proteolysis 1.9064E-3 6 2 1 6292
protein folding 2.2036E-3 6 78 2 6292
regulation of cell cycle process 2.3745E-3 6 81 2 6292
positive regulation of cellular component organization 2.8585E-3 6 3 1 6292
regulation of proteasomal ubiquitin-dependent protein catabolic process 2.8585E-3 6 3 1 6292
positive regulation of organelle organization 2.8585E-3 6 3 1 6292
positive regulation of ubiquitin-protein ligase activity 2.8585E-3 6 3 1 6292
positive regulation of protein ubiquitination 2.8585E-3 6 3 1 6292
positive regulation of protein catabolic process 2.8585E-3 6 3 1 6292
positive regulation of ligase activity 2.8585E-3 6 3 1 6292
positive regulation of protein modification process 2.8585E-3 6 3 1 6292
post-translational protein modification 3.1855E-3 6 357 3 6292
cell cycle phase 3.6971E-3 6 376 3 6292
positive regulation of cell cycle process 3.8098E-3 6 4 1 6292
positive regulation of cell cycle 3.8098E-3 6 4 1 6292
protein modification by small protein conjugation or removal 4.6544E-3 6 114 2 6292
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 4.7604E-3 6 5 1 6292
positive regulation of cellular catabolic process 5.7102E-3 6 6 1 6292
regulation of ubiquitin-protein ligase activity 5.7102E-3 6 6 1 6292
regulation of protein ubiquitination 5.7102E-3 6 6 1 6292
regulation of ligase activity 5.7102E-3 6 6 1 6292
M phase of mitotic cell cycle 5.8384E-3 6 128 2 6292
regulation of cell cycle 6.1086E-3 6 131 2 6292
positive regulation of cellular protein metabolic process 6.6592E-3 6 7 1 6292
positive regulation of catabolic process 6.6592E-3 6 7 1 6292
regulation of protein catabolic process 6.6592E-3 6 7 1 6292
regulation of protein modification process 6.6592E-3 6 7 1 6292
positive regulation of protein metabolic process 7.6075E-3 6 8 1 6292
regulation of proteolysis 7.6075E-3 6 8 1 6292
cell cycle process 7.8553E-3 6 490 3 6292
protein modification process 8.269E-3 6 499 3 6292
S phase 9.5019E-3 6 10 1 6292
S phase of mitotic cell cycle 9.5019E-3 6 10 1 6292
cell cycle 9.5389E-3 6 525 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

unfolded protein binding 1.3526E-3 6 61 2 6292
cyclin-dependent protein kinase activity 7.6075E-3 6 8 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle