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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 10 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear lumen 9.5088E-7 10 453 7 6292
nucleolus 8.8878E-6 10 211 5 6292
organelle lumen 1.2248E-5 10 660 7 6292
intracellular organelle lumen 1.2248E-5 10 660 7 6292
nucleus 1.2708E-5 10 2041 10 6292
membrane-enclosed lumen 1.8187E-5 10 700 7 6292
preribosome, large subunit precursor 8.1369E-5 10 9 2 6292
nuclear outer membrane 2.7608E-4 10 86 3 6292
nuclear part 3.6626E-4 10 1103 7 6292
nuclear membrane 3.9408E-4 10 97 3 6292
preribosome 1.2414E-3 10 34 2 6292
outer membrane 2.3071E-3 10 178 3 6292
organelle outer membrane 2.3071E-3 10 178 3 6292
nuclear envelope 3.1727E-3 10 199 3 6292
nuclear membrane-endoplasmic reticulum network 4.8992E-3 10 232 3 6292
membrane-bounded organelle 5.9511E-3 10 3771 10 6292
intracellular membrane-bounded organelle 5.9511E-3 10 3771 10 6292
nucleoplasm 7.0364E-3 10 264 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ribosome biogenesis 2.2334E-13 10 346 10 6292
ribonucleoprotein complex biogenesis 4.9117E-13 10 374 10 6292
ribosome assembly 1.7741E-10 10 64 6 6292
ribosomal large subunit biogenesis 1.9534E-10 10 65 6 6292
cellular component biogenesis 2.5149E-10 10 694 10 6292
organelle assembly 2.8288E-10 10 69 6 6292
ribonucleoprotein complex assembly 1.6615E-9 10 92 6 6292
cellular macromolecular complex assembly 1.0295E-7 10 182 6 6292
ribosomal large subunit assembly 3.1687E-7 10 41 4 6292
cellular macromolecular complex subunit organization 8.3957E-7 10 259 6 6292
ribosomal subunit assembly 1.0557E-6 10 55 4 6292
macromolecular complex assembly 1.3586E-6 10 281 6 6292
macromolecular complex subunit organization 5.5349E-6 10 357 6 6292
establishment of ribosome localization 7.3756E-6 10 26 3 6292
ribosome localization 7.3756E-6 10 26 3 6292
ribosomal subunit export from nucleus 7.3756E-6 10 26 3 6292
cellular component assembly 8.5951E-6 10 385 6 6292
establishment of organelle localization 7.2637E-5 10 55 3 6292
organelle localization 2.6667E-4 10 85 3 6292
processing of 27S pre-rRNA 2.6962E-4 10 16 2 6292
nuclear export 4.7031E-4 10 103 3 6292
nuclear transport 9.3003E-4 10 130 3 6292
nucleocytoplasmic transport 9.3003E-4 10 130 3 6292
organelle organization 3.5469E-3 10 1127 6 6292
cellular component organization 3.6048E-3 10 1582 7 6292
obsolete_biological_process 3.8312E-3 10 60 2 6292
traversing start control point of mitotic cell cycle 9.5019E-3 10 6 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

7S RNA binding 1.5893E-3 10 1 1 6292
5S rRNA binding 3.1764E-3 10 2 1 6292
GTPase activity 3.9577E-3 10 61 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle