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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 9 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U2 snRNP 1.6883E-26 9 13 9 6292
small nuclear ribonucleoprotein complex 5.5886E-19 9 63 9 6292
ribonucleoprotein complex 1.5187E-10 9 514 9 6292
nuclear part 1.5218E-7 9 1103 9 6292
macromolecular complex 5.3146E-6 9 1635 9 6292
nucleus 3.9292E-5 9 2041 9 6292
organelle part 1.0749E-4 9 2282 9 6292
intracellular organelle part 1.0749E-4 9 2282 9 6292
membrane-bounded organelle 9.9391E-3 9 3771 9 6292
intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 4.0875E-17 9 99 9 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4.4917E-17 9 100 9 6292
RNA splicing, via transesterification reactions 8.4663E-17 9 107 9 6292
RNA splicing 5.9908E-16 9 132 9 6292
mRNA processing 2.8146E-15 9 156 9 6292
mRNA metabolic process 4.9477E-14 9 213 9 6292
RNA processing 9.7721E-12 9 380 9 6292
spliceosome assembly 5.8572E-9 9 18 4 6292
RNA metabolic process 4.101E-8 9 954 9 6292
gene expression 5.9596E-7 9 1283 9 6292
nucleic acid metabolic process 1.4425E-6 9 1415 9 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6017E-6 9 1566 9 6292
ribonucleoprotein complex assembly 5.1011E-6 9 92 4 6292
cellular nitrogen compound metabolic process 1.0872E-5 9 1770 9 6292
nitrogen compound metabolic process 1.2092E-5 9 1791 9 6292
cellular macromolecular complex assembly 7.6181E-5 9 182 4 6292
cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
macromolecule metabolic process 1.3953E-4 9 2349 9 6292
cellular macromolecular complex subunit organization 3.0012E-4 9 259 4 6292
macromolecular complex assembly 4.1064E-4 9 281 4 6292
primary metabolic process 9.2081E-4 9 2896 9 6292
macromolecular complex subunit organization 1.0223E-3 9 357 4 6292
ribonucleoprotein complex biogenesis 1.2185E-3 9 374 4 6292
cellular component assembly 1.359E-3 9 385 4 6292
cellular metabolic process 1.3966E-3 9 3033 9 6292
metabolic process 2.004E-3 9 3157 9 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 7.1195E-12 9 367 9 6292
nucleic acid binding 1.5888E-9 9 666 9 6292
binding 6.4371E-7 9 1294 9 6292
U2 snRNA binding 1.4304E-3 9 1 1 6292
snRNA binding 7.1338E-3 9 5 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle