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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

membrane fraction 2.0111E-3 5 91 2 6292
insoluble fraction 2.0111E-3 5 91 2 6292
cell fraction 4.0056E-3 5 129 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of DNA replication initiation 1.0594E-5 5 7 2 6292
DNA replication checkpoint 1.0594E-5 5 7 2 6292
regulation of DNA replication initiation 1.4121E-5 5 8 2 6292
negative regulation of DNA replication 1.8149E-5 5 9 2 6292
regulation of DNA replication 5.2834E-5 5 15 2 6292
DNA integrity checkpoint 9.5453E-5 5 20 2 6292
negative regulation of DNA metabolic process 1.0547E-4 5 21 2 6292
mitotic sister chromatid cohesion 1.2698E-4 5 23 2 6292
regulation of DNA metabolic process 2.3279E-4 5 31 2 6292
sister chromatid cohesion 2.4823E-4 5 32 2 6292
DNA replication initiation 2.6416E-4 5 33 2 6292
cell cycle checkpoint 8.2043E-4 5 58 2 6292
mitotic sister chromatid segregation 1.0619E-3 5 66 2 6292
sister chromatid segregation 1.1603E-3 5 69 2 6292
protein thiol-disulfide exchange 1.5888E-3 5 2 1 6292
DNA-dependent DNA replication 1.6357E-3 5 82 2 6292
mitosis 2.6195E-3 5 104 2 6292
nuclear division 2.72E-3 5 106 2 6292
organelle fission 3.086E-3 5 113 2 6292
DNA replication 3.6472E-3 5 123 2 6292
chromosome segregation 3.9447E-3 5 128 2 6292
M phase of mitotic cell cycle 3.9447E-3 5 128 2 6292
regulation of cell cycle 4.1286E-3 5 131 2 6292
DNA topological change 6.3431E-3 5 8 1 6292
negative regulation of macromolecule biosynthetic process 7.2782E-3 5 175 2 6292
negative regulation of nitrogen compound metabolic process 7.6888E-3 5 180 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 7.6888E-3 5 180 2 6292
negative regulation of biosynthetic process 8.4546E-3 5 189 2 6292
negative regulation of cellular biosynthetic process 8.4546E-3 5 189 2 6292
negative regulation of macromolecule metabolic process 8.7174E-3 5 192 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor 3.1756E-3 5 4 1 6292
thiol oxidase activity 3.1756E-3 5 4 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle