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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 133.10
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC28
  • nucleus
  • cytoplasm
  • ribosome
  • G2/M transition of mitotic cell cycle
  • transcription
  • S phase of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • regulation of meiosis
  • protein amino acid phosphorylation
  • cyclin-dependent protein kinase activity
  • CLB1
  • nucleus
  • cytoplasm
  • G2/M transition of mitotic cell cycle
  • mitotic spindle organization in nucleus
  • meiotic G2/MI transition
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB2
  • nucleus
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • spindle
  • G2/M transition of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB3
  • nucleus
  • cytoplasm
  • G2/M transition of mitotic cell cycle
  • S phase of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB4
  • nucleus
  • cytoplasm
  • spindle pole body
  • G2/M transition of mitotic cell cycle
  • S phase of mitotic cell cycle
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB5
  • nucleus
  • spindle assembly
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • positive regulation of DNA replication
  • regulation of S phase of mitotic cell cycle
  • premeiotic DNA synthesis
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLB6
  • cellular_component
  • G1/S transition of mitotic cell cycle
  • positive regulation of DNA replication
  • regulation of S phase of mitotic cell cycle
  • premeiotic DNA synthesis
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLN1
  • nucleus
  • cytoplasm
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • CLN2
  • nucleus
  • cytoplasm
  • regulation of cyclin-dependent protein kinase activity
  • re-entry into mitotic cell cycle after pheromone arrest
  • cyclin-dependent protein kinase regulator activity
  • CLN3
  • nucleus
  • vacuole organization
  • G1/S transition of mitotic cell cycle
  • regulation of cell size
  • vacuole fusion, non-autophagic
  • regulation of cyclin-dependent protein kinase activity
  • cyclin-dependent protein kinase regulator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleus 2.7855E-4 10 2041 9 6292
    microtubule organizing center 4.2165E-3 10 63 2 6292
    spindle pole body 4.2165E-3 10 63 2 6292
    spindle pole 4.8974E-3 10 68 2 6292
    spindle 8.2701E-3 10 89 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of cyclin-dependent protein kinase activity 4.7239E-25 10 14 9 6292
    regulation of kinase activity 7.36E-22 10 26 9 6292
    regulation of protein kinase activity 7.36E-22 10 26 9 6292
    regulation of transferase activity 7.36E-22 10 26 9 6292
    regulation of phosphorylation 4.7454E-21 10 31 9 6292
    regulation of phosphate metabolic process 3.8332E-20 10 38 9 6292
    regulation of phosphorus metabolic process 3.8332E-20 10 38 9 6292
    regulation of catalytic activity 1.6656E-19 10 44 9 6292
    regulation of molecular function 1.6656E-19 10 44 9 6292
    regulation of cell cycle 1.0839E-17 10 131 10 6292
    phosphorylation 2.7076E-16 10 179 10 6292
    phosphorus metabolic process 3.3653E-15 10 229 10 6292
    phosphate metabolic process 3.3653E-15 10 229 10 6292
    interphase of mitotic cell cycle 1.0454E-13 10 97 8 6292
    interphase 1.0454E-13 10 97 8 6292
    S phase 7.7142E-13 10 10 5 6292
    S phase of mitotic cell cycle 7.7142E-13 10 10 5 6292
    G2/M transition of mitotic cell cycle 1.1458E-12 10 29 6 6292
    cell cycle 1.5113E-11 10 525 10 6292
    mitotic cell cycle 2.7423E-10 10 255 8 6292
    cell cycle process 9.1634E-10 10 490 9 6292
    regulation of cellular process 9.9931E-10 10 796 10 6292
    regulation of biological process 1.4148E-9 10 824 10 6292
    regulation of cellular metabolic process 2.0533E-9 10 536 9 6292
    regulation of metabolic process 2.4644E-9 10 547 9 6292
    cell cycle phase 6.1286E-9 10 376 8 6292
    biological regulation 6.8814E-8 10 1213 10 6292
    G1/S transition of mitotic cell cycle 7.1564E-7 10 50 4 6292
    positive regulation of DNA replication 2.2737E-6 10 2 2 6292
    regulation of S phase 6.8153E-6 10 3 2 6292
    regulation of S phase of mitotic cell cycle 6.8153E-6 10 3 2 6292
    positive regulation of DNA metabolic process 6.8153E-6 10 3 2 6292
    premeiotic DNA synthesis 2.2679E-5 10 5 2 6292
    regulation of cell cycle process 2.3113E-4 10 81 3 6292
    regulation of DNA replication 2.3612E-4 10 15 2 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    regulation of DNA metabolic process 1.0316E-3 10 31 2 6292
    meiotic G2/MI transition 1.5893E-3 10 1 1 6292
    spindle assembly 1.5893E-3 10 1 1 6292
    spindle organization 2.5693E-3 10 49 2 6292
    re-entry into mitotic cell cycle 4.7611E-3 10 3 1 6292
    re-entry into mitotic cell cycle after pheromone arrest 4.7611E-3 10 3 1 6292
    regulation of mitotic cell cycle 5.3288E-3 10 71 2 6292
    M phase 9.4842E-3 10 294 3 6292
    microtubule cytoskeleton organization 9.7663E-3 10 97 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cyclin-dependent protein kinase regulator activity 7.36E-22 10 26 9 6292
    protein kinase regulator activity 2.5877E-19 10 46 9 6292
    kinase regulator activity 4.8234E-19 10 49 9 6292
    enzyme regulator activity 3.6986E-13 10 207 9 6292

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