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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

FACT complex 1.0611E-6 7 2 2 6292
nucleoplasm part 1.6939E-6 7 245 5 6292
nucleoplasm 2.4553E-6 7 264 5 6292
organelle lumen 8.3215E-6 7 660 6 6292
intracellular organelle lumen 8.3215E-6 7 660 6 6292
histone acetyltransferase complex 1.0954E-5 7 44 3 6292
membrane-enclosed lumen 1.1789E-5 7 700 6 6292
alpha DNA polymerase:primase complex 2.2223E-5 7 7 2 6292
nuclear lumen 3.5214E-5 7 453 5 6292
nuclear replisome 1.6097E-4 7 18 2 6292
replisome 1.6097E-4 7 18 2 6292
nuclear replication fork 1.9969E-4 7 20 2 6292
transcription elongation factor complex 2.6548E-4 7 23 2 6292
replication fork 8.9439E-4 7 42 2 6292
protein-DNA complex 1.6447E-3 7 57 2 6292
nuclear part 2.5214E-3 7 1103 5 6292
nuclear chromatin 2.6853E-3 7 73 2 6292
protein complex 2.9048E-3 7 1137 5 6292
chromatin 2.9834E-3 7 77 2 6292
nucleus 5.8629E-3 7 2041 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription, DNA-dependent 1.657E-6 7 503 6 6292
RNA biosynthetic process 1.7576E-6 7 508 6 6292
transcription 2.8813E-6 7 552 6 6292
chromatin assembly or disassembly 5.4366E-6 7 35 3 6292
histone acetylation 5.928E-6 7 36 3 6292
RNA elongation from RNA polymerase II promoter 7.5768E-6 7 39 3 6292
RNA elongation 1.1731E-5 7 45 3 6292
protein amino acid acetylation 1.2543E-5 7 46 3 6292
chromatin modification 1.6125E-5 7 168 4 6292
chromatin silencing at telomere 2.1584E-5 7 55 3 6292
protein amino acid acylation 2.6695E-5 7 59 3 6292
chromatin organization 3.4121E-5 7 203 4 6292
RNA metabolic process 7.3069E-5 7 954 6 6292
covalent chromatin modification 8.8864E-5 7 88 3 6292
histone modification 8.8864E-5 7 88 3 6292
negative regulation of gene expression, epigenetic 1.3019E-4 7 100 3 6292
gene silencing 1.3019E-4 7 100 3 6292
regulation of gene expression, epigenetic 1.3019E-4 7 100 3 6292
chromatin silencing 1.3019E-4 7 100 3 6292
cellular macromolecule biosynthetic process 2.6203E-4 7 1187 6 6292
macromolecule biosynthetic process 2.6461E-4 7 1189 6 6292
gene expression 4.1171E-4 7 1283 6 6292
negative regulation of transcription, DNA-dependent 4.9559E-4 7 157 3 6292
negative regulation of RNA metabolic process 5.0493E-4 7 158 3 6292
negative regulation of transcription 5.6343E-4 7 164 3 6292
negative regulation of gene expression 5.6343E-4 7 164 3 6292
negative regulation of macromolecule biosynthetic process 6.8172E-4 7 175 3 6292
nucleic acid metabolic process 7.2556E-4 7 1415 6 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 7.404E-4 7 180 3 6292
negative regulation of nitrogen compound metabolic process 7.404E-4 7 180 3 6292
negative regulation of biosynthetic process 8.5405E-4 7 189 3 6292
negative regulation of cellular biosynthetic process 8.5405E-4 7 189 3 6292
negative regulation of macromolecule metabolic process 8.9429E-4 7 192 3 6292
transcription initiation from RNA polymerase II promoter 1.1199E-3 7 47 2 6292
negative regulation of cellular metabolic process 1.1455E-3 7 209 3 6292
negative regulation of metabolic process 1.1615E-3 7 210 3 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.3005E-3 7 1566 6 6292
cellular biosynthetic process 1.3053E-3 7 1567 6 6292
biosynthetic process 1.4816E-3 7 1602 6 6292
chromosome organization 1.6881E-3 7 555 4 6292
transcription initiation 1.7026E-3 7 58 2 6292
negative regulation of cellular process 1.9262E-3 7 250 3 6292
negative regulation of biological process 1.9938E-3 7 253 3 6292
cellular nitrogen compound metabolic process 2.6186E-3 7 1770 6 6292
macromolecular complex assembly 2.6978E-3 7 281 3 6292
nitrogen compound metabolic process 2.8003E-3 7 1791 6 6292
transcription from RNA polymerase II promoter 4.4591E-3 7 335 3 6292
macromolecular complex subunit organization 5.3413E-3 7 357 3 6292
post-translational protein modification 5.3413E-3 7 357 3 6292
regulation of transcription, DNA-dependent 5.3838E-3 7 358 3 6292
regulation of RNA metabolic process 5.5994E-3 7 363 3 6292
cellular metabolic process 6.026E-3 7 3033 7 6292
regulation of transcription 6.563E-3 7 384 3 6292
cellular component assembly 6.6113E-3 7 385 3 6292
metabolic process 7.9792E-3 7 3157 7 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1627E-3 7 415 3 6292
regulation of nitrogen compound metabolic process 8.218E-3 7 416 3 6292
regulation of gene expression 9.92E-3 7 445 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone binding 3.0541E-7 7 14 3 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle