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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
NOP53
  • nucleus
  • nucleolus
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • PBP4
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL32
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 2.5698E-11 10 101 7 6292
    cytosolic part 9.9194E-11 10 122 7 6292
    cytosolic large ribosomal subunit 1.1872E-10 10 60 6 6292
    ribosomal subunit 1.7519E-9 10 183 7 6292
    large ribosomal subunit 4.9413E-9 10 110 6 6292
    cytosol 3.7911E-8 10 284 7 6292
    ribosome 4.384E-8 10 290 7 6292
    ribonucleoprotein complex 2.253E-6 10 514 7 6292
    non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    intracellular non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    macromolecular complex 4.416E-3 10 1635 7 6292
    organelle part 6.1675E-3 10 2282 8 6292
    intracellular organelle part 6.1675E-3 10 2282 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.1286E-9 10 376 8 6292
    cellular protein metabolic process 2.2894E-5 10 1074 8 6292
    protein metabolic process 3.5183E-5 10 1136 8 6292
    cellular macromolecule biosynthetic process 4.9194E-5 10 1187 8 6292
    macromolecule biosynthetic process 4.9829E-5 10 1189 8 6292
    gene expression 8.885E-5 10 1283 8 6292
    cellular biosynthetic process 3.9961E-4 10 1567 8 6292
    biosynthetic process 4.7103E-4 10 1602 8 6292
    response to cycloheximide 1.5893E-3 10 1 1 6292
    response to cycloalkane 1.5893E-3 10 1 1 6292
    response to organic cyclic substance 1.5893E-3 10 1 1 6292
    regulation of translation 3.4634E-3 10 57 2 6292
    posttranscriptional regulation of gene expression 3.9577E-3 10 61 2 6292
    response to antibiotic 4.7611E-3 10 3 1 6292
    regulation of cellular protein metabolic process 4.8974E-3 10 68 2 6292
    regulation of protein metabolic process 5.7773E-3 10 74 2 6292
    cellular macromolecule metabolic process 6.225E-3 10 2285 8 6292
    macromolecule metabolic process 7.5629E-3 10 2349 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 6.195E-11 10 212 8 6292
    structural molecule activity 2.6832E-9 10 339 8 6292
    rRNA binding 2.6962E-4 10 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle