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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 7.8116E-12 9 101 7 6292
    cytosolic part 3.0242E-11 9 122 7 6292
    ribonucleoprotein complex 1.5187E-10 9 514 9 6292
    ribosomal subunit 5.3877E-10 9 183 7 6292
    cytosol 1.1829E-8 9 284 7 6292
    ribosome 1.3691E-8 9 290 7 6292
    cytosolic small ribosomal subunit 1.395E-7 9 38 4 6292
    90S preribosome 1.3628E-6 9 17 3 6292
    small ribosomal subunit 2.0114E-6 9 73 4 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    preribosome 1.1847E-5 9 34 3 6292
    non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    intracellular non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    cytosolic large ribosomal subunit 6.6496E-5 9 60 3 6292
    large ribosomal subunit 4.0454E-4 9 110 3 6292
    small nucleolar ribonucleoprotein complex 4.4137E-3 9 72 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.8752E-12 9 376 9 6292
    cellular protein metabolic process 1.1963E-7 9 1074 9 6292
    protein metabolic process 1.9861E-7 9 1136 9 6292
    cellular macromolecule biosynthetic process 2.9528E-7 9 1187 9 6292
    macromolecule biosynthetic process 2.9981E-7 9 1189 9 6292
    gene expression 5.9596E-7 9 1283 9 6292
    regulation of translation 7.375E-7 9 57 4 6292
    posttranscriptional regulation of gene expression 9.7183E-7 9 61 4 6292
    regulation of cellular protein metabolic process 1.5098E-6 9 68 4 6292
    regulation of protein metabolic process 2.125E-6 9 74 4 6292
    cellular biosynthetic process 3.6225E-6 9 1567 9 6292
    biosynthetic process 4.4215E-6 9 1602 9 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.4073E-4 9 13 2 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    metabolic process 2.004E-3 9 3157 9 6292
    regulation of gene expression 2.3358E-3 9 445 4 6292
    regulation of macromolecule biosynthetic process 2.5574E-3 9 456 4 6292
    ribosomal subunit assembly 2.5969E-3 9 55 2 6292
    regulation of cellular biosynthetic process 2.9058E-3 9 472 4 6292
    regulation of biosynthetic process 2.9286E-3 9 473 4 6292
    maturation of SSU-rRNA 2.9832E-3 9 59 2 6292
    regulation of macromolecule metabolic process 3.2863E-3 9 488 4 6292
    ribosome assembly 3.502E-3 9 64 2 6292
    regulation of primary metabolic process 3.9771E-3 9 514 4 6292
    organelle assembly 4.0601E-3 9 69 2 6292
    regulation of cellular metabolic process 4.6362E-3 9 536 4 6292
    regulation of metabolic process 4.9926E-3 9 547 4 6292
    ribonucleoprotein complex assembly 7.1217E-3 9 92 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.7387E-14 9 212 9 6292
    structural molecule activity 3.4568E-12 9 339 9 6292
    rRNA binding 2.1602E-4 9 16 2 6292
    RNA binding 1.1347E-3 9 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle