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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial oxoglutarate dehydrogenase complex 9.6394E-11 4 3 3 6292
oxoglutarate dehydrogenase complex 9.6394E-11 4 3 3 6292
nucleoid 2.4994E-7 4 26 3 6292
mitochondrial nucleoid 2.4994E-7 4 26 3 6292
mitochondrial matrix 5.9211E-7 4 176 4 6292
mitochondrial lumen 5.9211E-7 4 176 4 6292
mitochondrial part 3.2102E-5 4 475 4 6292
organelle lumen 1.2008E-4 4 660 4 6292
intracellular organelle lumen 1.2008E-4 4 660 4 6292
membrane-enclosed lumen 1.5203E-4 4 700 4 6292
non-membrane-bounded organelle 5.368E-4 4 959 4 6292
intracellular non-membrane-bounded organelle 5.368E-4 4 959 4 6292
mitochondrion 1.0175E-3 4 1125 4 6292
mitochondrial pyruvate dehydrogenase complex 3.8098E-3 4 6 1 6292
pyruvate dehydrogenase complex 3.8098E-3 4 6 1 6292
glycine cleavage complex 3.8098E-3 4 6 1 6292
macromolecular complex 4.5471E-3 4 1635 4 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

acetyl-CoA metabolic process 1.0967E-7 4 20 3 6292
2-oxoglutarate metabolic process 3.0316E-7 4 2 2 6292
coenzyme metabolic process 2.6694E-5 4 120 3 6292
tricarboxylic acid cycle 3.1744E-5 4 15 2 6292
acetyl-CoA catabolic process 3.1744E-5 4 15 2 6292
cofactor metabolic process 5.6502E-5 4 154 3 6292
coenzyme catabolic process 5.7381E-5 4 20 2 6292
cofactor catabolic process 6.9734E-5 4 22 2 6292
dicarboxylic acid metabolic process 1.3109E-4 4 30 2 6292
organic acid metabolic process 5.6477E-4 4 333 3 6292
oxoacid metabolic process 5.6477E-4 4 333 3 6292
carboxylic acid metabolic process 5.6477E-4 4 333 3 6292
cellular ketone metabolic process 6.3273E-4 4 346 3 6292
valine catabolic process 6.3573E-4 4 1 1 6292
valine metabolic process 6.3573E-4 4 1 1 6292
isoleucine catabolic process 6.3573E-4 4 1 1 6292
aerobic respiration 1.014E-3 4 83 2 6292
cellular catabolic process 1.084E-3 4 415 3 6292
acetyl-CoA biosynthetic process from pyruvate 1.2712E-3 4 2 1 6292
L-serine metabolic process 1.2712E-3 4 2 1 6292
L-serine biosynthetic process 1.2712E-3 4 2 1 6292
leucine catabolic process 1.2712E-3 4 2 1 6292
cellular respiration 1.3833E-3 4 97 2 6292
catabolic process 1.834E-3 4 496 3 6292
isoleucine metabolic process 1.9063E-3 4 3 1 6292
acetyl-CoA biosynthetic process 2.5411E-3 4 4 1 6292
branched chain family amino acid catabolic process 2.5411E-3 4 4 1 6292
energy derivation by oxidation of organic compounds 3.2394E-3 4 149 2 6292
glycine catabolic process 3.8098E-3 4 6 1 6292
serine family amino acid catabolic process 5.0773E-3 4 8 1 6292
glycine metabolic process 5.0773E-3 4 8 1 6292
leucine metabolic process 5.0773E-3 4 8 1 6292
generation of precursor metabolites and energy 5.5024E-3 4 195 2 6292
small molecule metabolic process 6.3905E-3 4 760 3 6292
serine family amino acid biosynthetic process 7.6087E-3 4 12 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

oxoglutarate dehydrogenase (succinyl-transferring) activity 3.0316E-7 4 2 2 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 3.0297E-6 4 5 2 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors 9.0505E-5 4 25 2 6292
dihydrolipoyl dehydrogenase activity 6.3573E-4 4 1 1 6292
S-succinyltransferase activity 6.3573E-4 4 1 1 6292
dihydrolipoyllysine-residue succinyltransferase activity 6.3573E-4 4 1 1 6292
succinyltransferase activity 1.2712E-3 4 2 1 6292
pyruvate dehydrogenase (acetyl-transferring) activity 2.5411E-3 4 4 1 6292
pyruvate dehydrogenase activity 2.5411E-3 4 4 1 6292
glycine dehydrogenase (decarboxylating) activity 3.8098E-3 4 6 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 3.8098E-3 4 6 1 6292
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 4.4437E-3 4 7 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors 7.6087E-3 4 12 1 6292
S-acyltransferase activity 8.2408E-3 4 13 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle