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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPF2
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • processing of 27S pre-rRNA
  • 5S rRNA binding
  • 7S RNA binding
  • rRNA binding
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL1A, RPL1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • RNA processing
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL8B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • translation
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.4602E-13 10 101 8 6292
    cytosolic large ribosomal subunit 5.871E-13 10 60 7 6292
    cytosolic part 6.9153E-13 10 122 8 6292
    ribosomal subunit 1.8849E-11 10 183 8 6292
    large ribosomal subunit 4.7364E-11 10 110 7 6292
    cytosol 6.5103E-10 10 284 8 6292
    ribosome 7.6979E-10 10 290 8 6292
    ribonucleoprotein complex 7.3162E-8 10 514 8 6292
    non-membrane-bounded organelle 3.7143E-7 10 959 9 6292
    intracellular non-membrane-bounded organelle 3.7143E-7 10 959 9 6292
    macromolecular complex 5.4804E-4 10 1635 8 6292
    organelle part 7.2492E-4 10 2282 9 6292
    intracellular organelle part 7.2492E-4 10 2282 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.4087E-11 10 376 9 6292
    cellular protein metabolic process 1.0138E-6 10 1074 9 6292
    protein metabolic process 1.6655E-6 10 1136 9 6292
    cellular macromolecule biosynthetic process 2.4546E-6 10 1187 9 6292
    macromolecule biosynthetic process 2.4913E-6 10 1189 9 6292
    gene expression 4.872E-6 10 1283 9 6292
    cellular biosynthetic process 2.8141E-5 10 1567 9 6292
    ribosomal large subunit assembly 2.9863E-5 10 41 3 6292
    biosynthetic process 3.4126E-5 10 1602 9 6292
    ribosomal subunit assembly 7.2637E-5 10 55 3 6292
    regulation of translation 8.0877E-5 10 57 3 6292
    posttranscriptional regulation of gene expression 9.9146E-5 10 61 3 6292
    ribosome assembly 1.1449E-4 10 64 3 6292
    ribosomal large subunit biogenesis 1.1993E-4 10 65 3 6292
    regulation of cellular protein metabolic process 1.3725E-4 10 68 3 6292
    organelle assembly 1.4337E-4 10 69 3 6292
    regulation of protein metabolic process 1.7664E-4 10 74 3 6292
    ribonucleoprotein complex assembly 3.3706E-4 10 92 3 6292
    cellular macromolecule metabolic process 7.3309E-4 10 2285 9 6292
    macromolecule metabolic process 9.2762E-4 10 2349 9 6292
    ribosome biogenesis 1.4482E-3 10 346 4 6292
    ribonucleoprotein complex biogenesis 1.9363E-3 10 374 4 6292
    cellular macromolecular complex assembly 2.4587E-3 10 182 3 6292
    primary metabolic process 5.4001E-3 10 2896 9 6292
    cellular macromolecular complex subunit organization 6.671E-3 10 259 3 6292
    cellular metabolic process 7.9165E-3 10 3033 9 6292
    macromolecular complex assembly 8.3691E-3 10 281 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.6009E-13 10 212 9 6292
    structural molecule activity 3.2934E-11 10 339 9 6292
    RNA binding 1.2975E-4 10 367 5 6292
    rRNA binding 2.6962E-4 10 16 2 6292
    7S RNA binding 1.5893E-3 10 1 1 6292
    nucleic acid binding 2.094E-3 10 666 5 6292
    5S rRNA binding 3.1764E-3 10 2 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle