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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 2.6411E-15 11 101 9 6292
    cytosolic part 1.5331E-14 11 122 9 6292
    ribosomal subunit 6.4136E-13 11 183 9 6292
    cytosol 3.4922E-11 11 284 9 6292
    ribosome 4.219E-11 11 290 9 6292
    ribonucleoprotein complex 1.2448E-10 11 514 10 6292
    preribosome 1.531E-9 11 34 5 6292
    90S preribosome 1.1899E-8 11 17 4 6292
    cytosolic large ribosomal subunit 2.9432E-8 11 60 5 6292
    cytosolic small ribosomal subunit 3.622E-7 11 38 4 6292
    large ribosomal subunit 6.3361E-7 11 110 5 6292
    non-membrane-bounded organelle 1.7653E-6 11 959 9 6292
    intracellular non-membrane-bounded organelle 1.7653E-6 11 959 9 6292
    small ribosomal subunit 5.1761E-6 11 73 4 6292
    macromolecular complex 1.1571E-5 11 1635 10 6292
    organelle part 2.6951E-3 11 2282 9 6292
    intracellular organelle part 2.6951E-3 11 2282 9 6292
    cytoplasmic part 5.2733E-3 11 2482 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.0204E-14 11 376 11 6292
    cellular protein metabolic process 3.4344E-9 11 1074 11 6292
    protein metabolic process 6.3855E-9 11 1136 11 6292
    cellular macromolecule biosynthetic process 1.0373E-8 11 1187 11 6292
    macromolecule biosynthetic process 1.0568E-8 11 1189 11 6292
    gene expression 2.4488E-8 11 1283 11 6292
    cellular biosynthetic process 2.2264E-7 11 1567 11 6292
    biosynthetic process 2.841E-7 11 1602 11 6292
    cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
    macromolecule metabolic process 1.9349E-5 11 2349 11 6292
    regulation of translation 1.1049E-4 11 57 3 6292
    posttranscriptional regulation of gene expression 1.3539E-4 11 61 3 6292
    regulation of cellular protein metabolic process 1.8726E-4 11 68 3 6292
    primary metabolic process 1.9438E-4 11 2896 11 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.145E-4 11 13 2 6292
    regulation of protein metabolic process 2.4083E-4 11 74 3 6292
    cellular metabolic process 3.2347E-4 11 3033 11 6292
    metabolic process 5.03E-4 11 3157 11 6292
    ribosome biogenesis 2.1778E-3 11 346 4 6292
    ribosomal large subunit assembly 2.1955E-3 11 41 2 6292
    ribonucleoprotein complex biogenesis 2.9012E-3 11 374 4 6292
    ribosomal subunit assembly 3.9232E-3 11 55 2 6292
    maturation of SSU-rRNA 4.5031E-3 11 59 2 6292
    ribosome assembly 5.2805E-3 11 64 2 6292
    ribosomal large subunit biogenesis 5.443E-3 11 65 2 6292
    organelle assembly 6.1157E-3 11 69 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.9231E-17 11 212 11 6292
    structural molecule activity 9.5087E-15 11 339 11 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle